Ligand reduced nicotinamide hypoxanthine dinucleotide

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Basic Ligand Information

Molecular Structure
Picture of reduced nicotinamide hypoxanthine dinucleotide (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C21H28N6O15P2
reduced nicotinamide hypoxanthine dinucleotide
WXWNHSQIXJHVJY-OBHXOGRVSA-N

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
glycerone phosphate + reduced nicotinamide hypoxanthine dinucleotide = sn-glycerol-3-phosphate + oxidized nicotinamide hypoxanthine dinucleotide
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(S)-lactate + nicotinamide hypoxanthine dinucleotide = pyruvate + reduced nicotinamide hypoxanthine dinucleotide
show the reaction diagram
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propanal + oxidized nicotinamide hypoxanthine dinucleotide + H2O = propionate + reduced nicotinamide hypoxanthine dinucleotide
show the reaction diagram
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propanal + oxidized nicotinamide hypoxanthine dinucleotide + H2O = propionate + reduced nicotinamide hypoxanthine dinucleotide
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
0.02 mM, 98% residual activity in presence of 0.05 mM NAD, pH 7.4
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Enzyme Kinetic Parameters

KM Value (1 result)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.005
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pH 7.4, 23°C, wild-type mutant enzyme and feedback-resistant mutant enzyme

References & Links

Links to other databases for reduced nicotinamide hypoxanthine dinucleotide

ChEBI
PubChem
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PubChem