Ligand chlorpyrifos

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Basic Ligand Information

Molecular Structure
Picture of chlorpyrifos (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C9H11ClNO3PS
chlorpyrifos
SBPBAQFWLVIOKP-UHFFFAOYSA-N
Synonyms:
(O,O)-diethyl-(3,5,6-trichloro)-2-pyridylphosphorothioate, chloropyrifos, O,O-diethyl-O-(3,5,6-trichloro-2-pyridyl)-phosphorothionate
Pathway Source
Pathways

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
chlorpyrifos + H2O = O,O-diethylphosphorothioate + 3,5,6-trichloropyridin-2-ol
show the reaction diagram
-

Substrate in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
chlorpyrifos + H2O = ?
show the reaction diagram
-
chlorpyrifos + H2O = ?
show the reaction diagram
-

Activator in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

Inhibitor in Enzyme-catalyzed Reactions (21 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
1 mM, 90% inhibition
-
i.e. Chloropyrifos
-
i.e. Chloropyrifos
-

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (8 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (8 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.36
-
pH 7.1, 50C

IC50 Value (5 results)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
0.0056
0.0148
pH 7.5, 37C
0.00000021
-
-
0.0076
-
in 0.5 mM Tris-HCl buffer, pH 7.4, at 22C

References & Links

Links to other databases for chlorpyrifos

ChEBI
PubChem
-
PubChem