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3 2-oxoglutarate + L-arginine + 3 O2 = 2 C2H4 + succinate + 7 CO2 + 3 H2O + guanidine + L-DELTA1-pyrroline-5-carboxylate
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2-oxoadipate + L-arginine + O2 = glutarate + CO2 + guanidine + (S)-1-pyrroline-5-carboxylate + H2O
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2-oxoglutarate + L-arginine + O2 = ethylene + succinate + CO2 + guanidine + (S)-1-pyrroline-5-carboxylate + H2O
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2-oxoglutarate + L-arginine + O2 = succinate + CO2 + guanidine + (S)-1-pyrroline-5-carboxylate
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2-oxoglutarate + L-arginine + O2 = succinate + CO2 + guanidine + (S)-1-pyrroline-5-carboxylate + H2O
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3 2-oxoglutarate + L-arginine + 3 O2 = 2 C2H4 + succinate + 7 CO2 + 3 H2O + guanidine + L-DELTA1-pyrroline-5-carboxylate
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L-proline + 2,6-dichlorophenolindophenol + H2O = (S)-1-pyrroline-5-carboxylate + reduced 2,6-dichlorophenolindophenol
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L-proline + 2,6-dichlorphenol-indophenol = (S)-1-pyrroline-5-carboxylate + reduced 2,6-dichlorphenol-indophenol
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L-proline + a quinone = (S)-1-pyrroline-5-carboxylate + a quinol
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L-proline + acceptor + H2O = (S)-1-pyrroline-5-carboxylate + reduced acceptor
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L-proline + acceptor = (S)-1-pyrroline-5-carboxylate + reduced acceptor
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L-proline + cytochrome c = (S)-1-pyrroline-5-carboxylate + reduced cytochrome c
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L-proline + FAD + H2O = (S)-1-pyrroline-5-carboxylate + FADH2
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L-proline + ferricyanide + H2O = (S)-1-pyrroline-5-carboxylate + ferrocyanide
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L-proline + NAD+ + H2O = (S)-1-pyrroline-5-carboxylate + NADH
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L-proline + NAD+ = (S)-1-pyrroline-5-carboxylate + NADH
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L-proline + oxidized phenazine methosulfate = (S)-1-pyrroline-5-carboxylate + reduced phenazine methosulfate
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L-proline + 2,6-dichlorophenolindophenol + H2O = (S)-1-pyrroline-5-carboxylate + reduced 2,6-dichlorophenolindophenol
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L-proline + 2,6-dichlorophenolindophenol = (S)-1-pyrroline-5-carboxylate + reduced 2,6-dichlorophenolindophenol
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L-proline + acceptor + H2O = (S)-1-pyrroline-5-carboxylate + reduced acceptor
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L-proline + acceptor = (S)-1-pyrroline-5-carboxylate + reduced acceptor
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L-proline + cytochrome c + H2O = (S)-1-pyrroline-5-carboxylate + reduced cytochrome c
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L-proline + FAD = (S)-1-pyrroline-5-carboxylate + FADH2
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L-proline + H2O = (S)-1-pyrroline-5-carboxylate + H2O2
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L-proline + menadione = (S)-1-pyrroline-5-carboxylate + menadiol
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L-proline + oxidized 2,6-dichlorophenolindophenol + H2O = (S)-1-pyrroline-5-carboxylate + reduced 2,6-dichlorophenolindophenol
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L-proline + oxidized phenazine methosulfate = (S)-1-pyrroline-5-carboxylate + reduced phenazine methosulfate
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L-proline + p-iodonitrotetrazolium + H2O = (S)-1-pyrroline-5-carboxylate + reduced p-iodonitrotetrazolium
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trans-4-hydroxy-L-proline = (S)-1-pyrroline-5-carboxylate + H2O
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Identity of proline dehydrogenase and delta1-pyrroline-5-carboxylic acid reductase in Clostridium sporogenes
1978
Costilow, R.N.; Cooper, D.
J. Bacteriol.
134
139-146
Membrane association of proline dehydrogenase in Escherichia coli is redox dependent
1987
Wood, J.M.
Proc. Natl. Acad. Sci. USA
84
373-377
Proline dehydrogenase from Escherichia coli K12. Reconstitution of a functional membrane association
1984
Graham, S.B.; Stephenson, J.T.; Wood, J.M.
J. Biol. Chem.
259
2656-2661
Purification and properties of the bifunctional proline dehydrogenase/1-pyrroline-5-carboxylate dehydrogenase from Pseudomonas aeruginosa
1982
Meile, L.; Leisinger, T.
Eur. J. Biochem.
129
67-75
Proline oxidation in corn mitochondia
1982
Elthon, T.E.; Stewart, C.R.
Plant Physiol.
70
567-572
Respiratory and enzymatic properties of squid heart mitochondria
1981
Mommsen, T.P.; Hochachka, P.W.
Eur. J. Biochem.
120
345-350
Membrane-bound proline dehydrogenase from Escherichia coli. Solubilization, purification, and characterization
1978
Scarpulla, R.C.; Soffer, R.L.
J. Biol. Chem.
253
5997-6001
Solubilization of proline dehydrogenase from rat liver mitochondria
1971
Kramar, R.
Hoppe-Seyler's Z. Physiol. Chem.
352
1267-1270
The activities of proline dehydrogenase, glutamate dehydrogenase, aspartate-oxoglutarate aminotransferase and alanine-oxoglutarate aminotransferase in some insect flight muscles
1970
Crabtree, B.; Newsholme, E.A.
Biochem. J.
117
1019-1021
Thioester hydrolysis and C-C bond formation by carboxymethylproline synthase from the crotonase superfamily
2008
Batchelar, E.T.; Hamed, R.B.; Ducho, C.; Claridge, T.D.; Edelmann, M.J.; Kessler, B.; Schofield, C.J.
Angew. Chem. Int. Ed. Engl.
47
9322-93225
Carboxymethylproline synthase from Pectobacterium carotorova: a multifaceted member of the crotonase superfamily
2004
Gerratana, B.; Arnett, S.O.; Stapon, A.; Townsend, C.A.
Biochemistry
43
15936-15945
Carboxymethylproline synthase catalysed syntheses of functionalised N-heterocycles
2010
Hamed, R.B.; Mecinovic, J.; Ducho, C.; Claridge, T.D.; Schofield. C.J.
Chem. Commun. (Camb. )
46
1413-1415
Carboxymethylproline synthase (CarB), an unusual carbon-carbon bond-forming enzyme of the crotonase superfamily involved in carbapenem biosynthesis
2004
Sleeman, M.C.; Schofield, C.J.
J. Biol. Chem.
279
6730-6736
Structural and mechanistic studies on carboxymethylproline synthase (CarB), a unique member of the crotonase superfamily catalyzing the first step in carbapenem biosynthesis
2005
Sleeman, M.C.; Sorensen, J.L.; Batchelar, E.T.; McDonough, M.A.; Schofield, C.J.
J. Biol. Chem.
280
34956-34965
Analysis of bacterial carbapenem antibiotic production genes reveals a novel beta-lactam biosynthesis pathway
1996
McGowan, S.J.; Sebaihia, M.; Porter, L.E.; Stewart, G.S.; Williams, P.; Bycroft, B.W.; Salmond, G.P.
Mol. Microbiol.
22
415-426
Stereoselective C-C bond formation catalysed by engineered carboxymethylproline synthases
2011
Hamed, R.B.; Gomez-Castellanos, J.R.; Thalhammer, A.; Harding, D.; Ducho, C.; Claridge, T.D.; Schofield. C.J.
Nat. Chem.
3
365-371
Structure-based molecular design for thermostabilization of N-acetyltransferase Mpr1 involved in a novel pathway of L-arginine synthesis in yeast
2015
Nasuno, R.; Hirase, S.; Norifune, S.; Watanabe, D.; Takagi, H.
J. Biochem.
159
271-277
Structural and functional analysis of the yeast n-Acetyltransferase mpr1 involved in oxidative stress tolerance via proline metabolism
2013
Nasuno, R.; Hirano, Y.; Itoh, T.; Hakoshima, T.; Hibi, T.; Takagi, H.
Proc. Natl. Acad. Sci. USA
110
11821-11826