Ligand 2-formylglutarate

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Basic Ligand Information

Molecular Structure
Picture of 2-formylglutarate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C6H8O5
2-formylglutarate
ZRFCKBDKFHYMHU-ZRSNTTJMSA-N

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-formylglutarate + NADH + H+ = 2-hydroxymethylglutarate + NAD+
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
6-oxo-1,4,5,6-tetrahydronicotinate + H2O = 2-formylglutarate + NH3
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-formylglutarate + NADH + H+ = 2-hydroxymethylglutarate + NAD+
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-hydroxymethylglutarate + NAD+ = 2-formylglutarate + NADH + H+
show the reaction diagram
-
-
6-oxo-1,4,5,6-tetrahydronicotinate + H2O = 2-formylglutarate + NH3
show the reaction diagram
-
-

Enzyme Kinetic Parameters

References & Links

Links to other databases for 2-formylglutarate

ChEBI
PubChem
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PubChem