Ligand dUDP

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Basic Ligand Information

Molecular Structure
Picture of dUDP (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C9H14N2O11P2
dUDP
JGDHLPIJGRWPJT-IRXDYDNUSA-N
Synonyms:
2'-deoxy-UDP, 2'-dUDP, D-dUDP, deoxyuridine diphosphate


Show all pahtways known for Show all BRENDA pathways known for dUDP

Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
UDP + thioredoxin = 2'-dUDP + thioredoxin disulfide + H2O
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ATP + dUMP = ADP + dUDP
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dUTP + H2O = dUDP + phosphate
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Substrate in Enzyme-catalyzed Reactions (25 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
dUDP + sucrose = dUDP-alpha-D-glucose + D-fructose
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Product in Enzyme-catalyzed Reactions (27 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
UDP + reduced thioredoxin = dUDP + oxidized thioredoxin + H2O
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dUDP-alpha-D-glucose + D-fructose = dUDP + sucrose
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dUDPgalactose + D-glucose = lactose + dUDP
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UDP-beta-L-vancosamine + desvancosaminyl-vancomycin = dUDP + vancomycin
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dUTP + deoxyguanosine = dUDP + dGMP
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dUTP + 4-methyl-5-(2-hydroxyethyl)thiazole = dUDP + 4-methyl-5-(2-phosphonooxyethyl)thiazole
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dUTP + D-galactose = dUDP + alpha-D-galactose 1-phosphate
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dUTP + 2'-deoxycytidine = dUDP + 2'-deoxy-CMP
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ATP + dUMP = ADP + dUDP
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ATP + dUMP = ADP + dUDP
show the reaction diagram
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ATP + dUMP = ADP + dUDP
show the reaction diagram
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ATP + dUMP = ADP + dUDP
show the reaction diagram
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dUTP + H2O = dUDP + phosphate
show the reaction diagram
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dUTP + H2O = dUDP + phosphate
show the reaction diagram
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dUTP + H2O = dUDP + phosphate
show the reaction diagram
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dUTP + H2O + closed Cl- channel = dUDP + phosphate + open Cl- channel
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Inhibitor in Enzyme-catalyzed Reactions (49 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
product inhibition
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weak
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with dTTP or dUTP as substrate
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3D Structure of Enzyme-Ligand-Complex (PDB) (60 results)

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
65
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pH 8, 25°C

KM Value (7 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

References & Links

Links to other databases for dUDP

ChEBI
PubChem
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PubChem