Ligand 3-fluoro 4-nitrophenyl diethyl phosphate
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Basic Ligand Information
Molecular Structure

C10H13FNO6P
3-fluoro 4-nitrophenyl diethyl phosphate
JNMCHKJZUGLPFW-UHFFFAOYSA-N
3-fluoro-4-nitrophenyl diethyl phosphate, diethyl 3-fluoro-4-nitrophenyl phosphate
Roles as Enzyme Ligand
Substrate in Enzyme-catalyzed Reactions (2 results)
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3-fluoro-4-nitrophenyl diethyl phosphate + H2O = 3-fluoro-4-nitrophenol + diethyl phosphate
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diethyl 3-fluoro-4-nitrophenyl phosphate + H2O = diethyl phosphate + 3-fluoro-4-nitrophenol
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Enzyme Kinetic Parameters
kcat Value (Turnover Number) (3 results)
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107
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pH and temperature not specified in the publication
11680
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pH 8.0, genetic variant PON1 G2E6
KM Value (2 results)
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0.25
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pH and temperature not specified in the publication
References & Links
Literature References (2)
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Structure-reactivity studies of serum paraoxonase PON1 suggest that its native activity is lactonase
2005
Khersonsky, O.; Tawfik, D.S.
Biochemistry
44
6371-6382
Transition State Analysis of the Reaction Catalyzed by the Phosphotriesterase from Sphingobium sp. TCM1
2019
Bigley, A.N.; Xiang, D.F.; Narindoshvili, T.; Burgert, C.W.; Hengge, A.C.; Raushel, F.M.
Biochemistry
58
1246-1259
Links to other databases for 3-fluoro 4-nitrophenyl diethyl phosphate