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Ligand S-ubiquitinyl-[cullin-RING-E3-ubiquitin-carrier protein]-L-cysteine

Basic Ligand Information

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Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

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Show Natural Substrate (1 entry)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.3.2.B13

S-ubiquitinyl-[cullin-RING-E3-ubiquitin-carrier protein]-L-cysteine + [acceptor protein]-L-lysine = [cullin-RING-E3-ubiquitin-carrier protein]-L-cysteine + N6-ubiquitinyl-[acceptor protein]-L-lysine

735947, 737273

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Substrate in Enzyme-catalyzed Reactions (1 result)

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Show Substrate (1 entry)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.3.2.B13

S-ubiquitinyl-[cullin-RING-E3-ubiquitin-carrier protein]-L-cysteine + [acceptor protein]-L-lysine = [cullin-RING-E3-ubiquitin-carrier protein]-L-cysteine + N6-ubiquitinyl-[acceptor protein]-L-lysine

735947, 737273

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Enzyme Kinetic Parameters

References & Links

Literature References (2)

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Show Reference (2 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

735947

23824602

Phage display to identify Nedd8-mimicking peptides as inhibitors of the Nedd8 transfer cascade

2013

Zhao, B.; Zhang, K.; Villhauer, E.; Bhuripanyo, K.; Kiyokawa, H.; Schindelin, H.; Yin, J.

ChemBioChem

14

1323-1330

737273

25661653

Insights into cullin-RING E3 ubiquitin ligase recruitment: Structure of the VHL-EloBC-Cul2 complex

2015

Nguyen, H.; Yang, H.; Fribourgh, J.; Wolfe, L.; Xiong, Y.

Structure

23

441-449

Links to other databases for S-ubiquitinyl-[cullin-RING-E3-ubiquitin-carrier protein]-L-cysteine

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Show Links (1 entry)