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BRENDA support

Ligand benzimidazole

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Basic Ligand Information

Molecular Structure
Picture of benzimidazole (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C7H6N2
benzimidazole
HYZJCKYKOHLVJF-UHFFFAOYSA-N
Synonyms:
1-Benzimidazole

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
nicotinic acid mononucleotide + benzimidazole = 1-alpha-D-ribofuranosylbenzimidazole 5'-phosphate + nicotinic acid
show the reaction diagram

Substrate in Enzyme-catalyzed Reactions (10 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Inhibitor in Enzyme-catalyzed Reactions (18 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
IC50: more than 0.15 mM
-
0.001 mM, 72% inhibition
-

3D Structure of Enzyme-Ligand-Complex (PDB) (21 results)

Enzyme Kinetic Parameters

KM Value (2 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

Ki Value (10 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

IC50 Value (2 results)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
0.15
-
IC50: more than 0.15 mM
0.000044
-
pH and temperature not specified in the publication, recombinant enzyme

References & Links

Links to other databases for benzimidazole

ChEBI
PubChem
ChEBI
PubChem