Ligand geranyl diphosphate

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Basic Ligand Information

Molecular Structure
Picture of geranyl diphosphate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C10H20O7P2
geranyl diphosphate
GVVPGTZRZFNKDS-JXMROGBWSA-N
Synonyms:
(2E)-geranyl diphosphate, (E)-geraniol diphosphate, (E)-geranyl diphosphate, an all-trans-polyprenyl diphosphate, a polyprenyl diphosphate, geranyl-diphosphate, geranyldiphosphate
Pathway Source
Pathways


Show all pahtways known for Show all BRENDA pathways known for geranyl diphosphate

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (81 results)

EC NUMBER
LITERATURE
REACTION DIAGRAM
PROVEN IN VIVO REACTION
ENZYME 3D STRUCTURE
show the reaction diagram
S-adenosyl-L-methionine + geranyl diphosphate = S-adenosyl-L-homocysteine + (E)-2-methylgeranyl diphosphate
-
show the reaction diagram
geranyl diphosphate + flaviolin = 3-linalylflaviolin + diphosphate
-
show the reaction diagram
geranyl diphosphate + 2-O-methyl-3-methylflaviolin = diphosphate + (E)-7-((3,7-dimethylocta-2,6-dien-1-yl)oxy)-5-hydroxy-2-methoxy-3-methylnaphthalene-1,4-dione + 6-prenyl-2-methoxy-3-methylflaviolin
-
show the reaction diagram
geranyl diphosphate + 2-O-methyl-3-methylflaviolin = diphosphate + 7-[[(2E)-3,7-dimethylocta-2,6-dien-1-yl]oxy]-5-hydroxy-2-methoxy-3-methylnaphthalene-1,4-dione
-
show the reaction diagram
3-[(E)-2-isocyanoethenyl]-1H-indole + geranyl diphosphate = 2-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-3-[(Z)-2-isocyanoethenyl]-1H-indole + 3-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-3-[(Z)-2-isocyanoethenyl]-3H-indole
-
show the reaction diagram
a polyprenyl diphosphate + 4-hydroxybenzoate = diphosphate + a 4-hydroxy-3-polyprenylbenzoate
-
show the reaction diagram
geranyl diphosphate + 7 isopentenyl diphosphate = 7 diphosphate + all-trans-nonaprenyl diphosphate
-
show the reaction diagram
geranyl diphosphate + n isopentenyl diphosphate = n diphosphate + di-trans,poly-cis-polyprenyl diphosphate
-
show the reaction diagram
geranyl diphosphate + 4-hydroxybenzoate = 3-geranyl-4-hydroxybenzoate + diphosphate
-
show the reaction diagram
selenophosphate + geranyl diphosphate + 5-methylaminomethyl-2-thiouridine34 in tRNA + H2O = 5-methylaminomethyl-2-selenouridine34 in tRNA + (2E)-3,7-dimethylocta-2,6-diene-1-thiol + diphosphate + phosphate
-
show the reaction diagram
geranyl diphosphate + H2O = geraniol + diphosphate
-
show the reaction diagram
geranyl-diphosphate + H2O = ?
-
show the reaction diagram
geranyl diphosphate + H2O = geranyl phosphate + phosphate
show the reaction diagram
geranyl diphosphate = (-)-endo-fenchol + diphosphate
-
show the reaction diagram
geranyl diphosphate = tricyclene + diphosphate
-
show the reaction diagram
geranyl diphosphate = (E)-beta-ocimene + diphosphate
-
show the reaction diagram
geranyl diphosphate = (+)-car-3-ene + diphosphate
-
show the reaction diagram
geranyl diphosphate + H2O = 1,8-cineole + diphosphate
-
show the reaction diagram
geranyl diphosphate + H2O = cis-sabinene hydrate + diphosphate
-
show the reaction diagram
geranyl diphosphate = (+)-sabinene + diphosphate
-
show the reaction diagram
geranyl diphosphate + H2O = alpha-terpineol + diphosphate
-
show the reaction diagram
geranyl diphosphate = terpinolene + diphosphate
-
show the reaction diagram
geranyl diphosphate = gamma-terpinene + diphosphate
-
show the reaction diagram
geranyl diphosphate = alpha-terpinene + diphosphate
-
show the reaction diagram
geranyl diphosphate = camphene + diphosphate
-
show the reaction diagram
geranyl diphosphate = beta-pinene + diphosphate
-
show the reaction diagram
geranyl diphosphate = alpha-pinene + diphosphate
-
show the reaction diagram
geranyl diphosphate = beta-pinene + diphosphate
-
show the reaction diagram
geranyl diphosphate = beta-thujene + diphosphate
-
show the reaction diagram
geranyl diphosphate + H2O = (3R)-linalool + diphosphate
-
show the reaction diagram
geranyl diphosphate + H2O = (3S)-linalool + diphosphate
-
show the reaction diagram
geranyl diphosphate = (4S)-beta-phellandrene + diphosphate
-
show the reaction diagram
geranyl diphosphate = (Z)-beta-ocimene + diphosphate
-
show the reaction diagram
geranyl diphosphate = (-)-bornyl diphosphate
-

In Vivo Product in Enzyme-catalyzed Reactions (9 results)

EC NUMBER
LITERATURE
REACTION DIAGRAM
PROVEN IN VIVO REACTION
ENZYME 3D STRUCTURE
-
show the reaction diagram
dimethylallyl diphosphate + isopentenyl diphosphate = diphosphate + geranyl diphosphate
-
-
show the reaction diagram
dimethylallyl diphosphate + isopentenyl diphosphate = diphosphate + geranyl diphosphate
-
-
show the reaction diagram
ATP + geranyl phosphate = ADP + geranyl diphosphate
-

Substrate in Enzyme-catalyzed Reactions (222 results)

EC NUMBER
LITERATURE
REACTION DIAGRAM
REACTION
ENZYME 3D STRUCTURE
show the reaction diagram
S-adenosyl-L-methionine + geranyl diphosphate = S-adenosyl-L-homocysteine + (E)-2-methylgeranyl diphosphate
-
show the reaction diagram
geranyl diphosphate + (2Z)-3-(1H-indol-3-yl)prop-2-enenitrile = diphosphate + (2Z)-3-(2-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-1H-indol-3-yl)prop-2-enenitrile + (2E)-3-(2-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-3H-indol-3-yl)prop-2-enenitrile
-
show the reaction diagram
geranyl diphosphate + ADP = ?
-
show the reaction diagram
geranyl diphosphate + homogentisate = diphosphate + (3-geranyl-2,5-dihydroxyphenyl)acetate
-
show the reaction diagram
3-[(E)-2-isocyanoethenyl]-1H-indole + geranyl diphosphate = 2-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-3-[(Z)-2-isocyanoethenyl]-1H-indole + 3-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-3-[(Z)-2-isocyanoethenyl]-3H-indole
-
show the reaction diagram
geranyl diphosphate + ADP = diphosphate + N6-geranyl-ADP
-
show the reaction diagram
geranyl diphosphate + 4 isopentenyl diphosphate = 4 diphosphate + all-trans-hexaprenyl diphosphate
show the reaction diagram
Geranyl diphosphate = ?
-
show the reaction diagram
geranyl diphosphate + L-tryptophan = diphosphate + ?
-
show the reaction diagram
geranyl diphosphate + dansyl-GCVLS = dansyl-G-(S-geranyl)CVLS + diphosphate
-
show the reaction diagram
geranyl diphosphate + 3 isopentenyl diphosphate = (2E,6E,10E,14E)-geranylfarnesyl diphosphate + 3 diphosphate
-
show the reaction diagram
geranyl diphosphate + 4 isopentenyl diphosphate = 4 diphosphate + all-trans-hexaprenyl diphosphate
-
show the reaction diagram
geranyl diphosphate + 4 isopentenyl diphosphate = 4 diphosphate + all-trans-hexaprenyl diphosphate
-
show the reaction diagram
geranyl diphosphate + 7 isopentenyl diphosphate = 7 diphosphate + all-trans-nonaprenyl diphosphate
-
show the reaction diagram
geranyl diphosphate + isopentenyl diphosphate = diphosphate + decaprenyl diphosphate + nonaprenyl diphosphate + octaprenyl diphosphate
-
show the reaction diagram
geranyl diphosphate + n isopentenyl diphosphate = n diphosphate + di-trans,poly-cis-polyprenyl diphosphate
-
show the reaction diagram
geranyl diphosphate + n isopentenyl diphosphate = n diphosphate + trans,poly-cis-polyprenyl diphosphate
-
show the reaction diagram
geranyl diphosphate + isopentenyl diphosphate = ?
-
show the reaction diagram
geranyl diphosphate + 4-hydroxybenzoate = 3-geranyl-4-hydroxybenzoate + diphosphate
-
show the reaction diagram
geranyl diphosphate + 9 isopentenyl diphosphate = 9 diphosphate + monotrans,nonacis-undecaprenyl diphosphate
-
show the reaction diagram
pinostrobin chalcone + geranyl diphosphate = pinostrobin + ?
-
show the reaction diagram
geranyl diphosphate + H2O = geraniol + ?
-
show the reaction diagram
geranyl diphosphate + H2O = geraniol + phosphate
-
show the reaction diagram
geranyl diphosphate + H2O = geraniol + diphosphate
-
show the reaction diagram
geranyl diphosphate + H2O = geraniol + diphosphate
-
show the reaction diagram
geranyl diphosphate + H2O = geraniol + diphosphate
-
show the reaction diagram
geranyldiphosphate + H2O = ?
-
show the reaction diagram
geranyl diphosphate + H2O = geranyl phosphate + phosphate
show the reaction diagram
geranyl diphosphate = (S)-(-)-limonene + diphosphate
-
show the reaction diagram
geranyl diphosphate = (S)-(-)-limonene + diphosphate
-
show the reaction diagram
(2E)-geranyl diphosphate + H2O = geraniol + diphosphate
-
show the reaction diagram
geranyl diphosphate = tricyclene + diphosphate
-
show the reaction diagram
geranyl diphosphate = (E)-beta-ocimene + diphosphate
-
show the reaction diagram
geranyl diphosphate = (+)-car-3-ene + diphosphate
-
show the reaction diagram
geranyl diphosphate = terpinolene + diphosphate
-
show the reaction diagram
geranyl diphosphate = alpha-terpinene + diphosphate
-
show the reaction diagram
geranyl diphosphate + H2O = limonene + diphosphate
-
show the reaction diagram
(E)-geranyl diphosphate = ?
-
show the reaction diagram
(E)-geraniol diphosphate = ?
-
show the reaction diagram
geranyl diphosphate = beta-thujene + diphosphate
-
show the reaction diagram
geranyl diphosphate = myrcene + (E)-beta-ocimene + (Z)-beta-ocimene + diphosphate
-
show the reaction diagram
geranyl diphosphate + H2O = (3R)-linalool + diphosphate
-
show the reaction diagram
geranyl diphosphate + H2O = ? + diphosphate
-
show the reaction diagram
geranyl diphosphate = ? + diphosphate
-
show the reaction diagram
geranyl diphosphate = geraniol + linalool + diphosphate
-
show the reaction diagram
Geranyl diphosphate = ?
-
show the reaction diagram
Geranyl diphosphate = ?
-
show the reaction diagram
geranyl diphosphate = (Z)-beta-ocimene + diphosphate
-
show the reaction diagram
geranyl diphosphate = (S)-beta-bisabolene + (S)-beta-macrocarpene
-
show the reaction diagram
geranyl diphosphate = (-)-bornyl diphosphate
-
show the reaction diagram
ATP + geranyl diphosphate = adenosine 5'-geranyl triphosphate + diphosphate
-
show the reaction diagram
ATP + geranyl diphosphate = geranyl-triphospho(5')adenosine + diphosphate
-

Product in Enzyme-catalyzed Reactions (24 results)

EC NUMBER
LITERATURE
REACTION DIAGRAM
REACTION
ENZYME 3D STRUCTURE
show the reaction diagram
dimethylallyl diphosphate + isopentenyl diphosphate = (E,E)-farnesyl diphosphate + (E)-geranyl diphosphate
-
-
show the reaction diagram
ATP + geranyl phosphate = ADP + geranyl diphosphate
-

Inhibitor in Enzyme-catalyzed Reactions (19 results)

COMMENTARY
EC NUMBER
LITERATURE
ENZYME 3D STRUCTURE
0.3 mM, approx. 10% inhibition
-
potent inhibitor
-
competitive with ATP
-
0.01 mM, 55% inhibition
-
30% inhibition
-
0.1 mM: 16% inhibition of soluble FDPase activity, 0.05 mM: 26% inhibition of microsomal FDPase activity, competitive
-
FDPase activity, 0.1 mM, 50% inhibition, no inhibition of GGDPase
-
16% inhibition of soluble enzyme at 0.1 mM. 26% inhibition of microsomal enzyme at 0.05 mM
-
substrate inhibition above 0.05 mM
substrate inhibition above 0.01 mM; substrate inhibition above 0.01 mM
-

3D Structure of Enzyme-Ligand-Complex (PDB) (151 results)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (85 results)

COMMENTARY
EC NUMBER
LITERATURE
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
pH and temperature not specified in the publication
0.0075
-
pH 7.0, 37°C, recombinant enzyme
0.0075
-
at pH 7.5 and 30°C
0.1
-
pH 7.9, 37°C
0.2
-
at pH 7.5% and 30°C
43.5
-
with phenyl(2,4,6-trihydroxyphenyl)methanone as cosubstrate, at pH 7.5 and 37°C
0.126
-
with 3 as cosubstrate, at pH 7.5 and 37°C
0.126
-
pH 7.7, 37°C, recombinant PvGGPPS
0.5
-
-
2.1
-
25°C, pH 7.5
1.7
-
apparent turnover number
0.004
-
pH 7.5, 37°C
pH 7.4, 37°C
0.065
-
pH 7.9, 37°C
pH 7.5, 37°C
0.067
-
pH 8.5, 37°C, wild-type enzyme
0.8
-
pH 8.5, 37°C, Ser35 truncated mutant
0.6
-
pH 8.5, 37°C, Met44-truncated mutant
1
-
pH 7.5, 38°C, recombinant His-tagged enzyme
3.8
-
accession Columbia, 30°C, pH not specified in the publication
0.034
-
pH 7.4, 30°C, proteins from both susceptible and resistant plants have similar kinetic parameters
2.21
-
recombinant His-tagged enzyme, pH 7.2, temperature not specified in the publication
2.07
-
wild-type, 30°C, pH not specified in the publication
0.098
-
mutant L596F, 30°C, pH not specified in the publication
0.643
-
mutant N338I, pH 7.0, 22°C
0.096
-
mutant N338I/A339T/G447S/I449P/P450T, pH 7.0, 22°C
0.0043
-
recombinant wild-type enzyme, pH and temperature not specified in the publication
0.00041
-
temperature not specified in the publication, pH not specified in the publication
0.001
-
recombinant mutant F266V, pH and temperature not specified in the publication
0.00008
-
mutant N338S, pH 7.0, 22°C
0.022
-
mutant N338I/A339T/G447S, pH 7.0, 22°C
0.0043
-
recombinant mutant F266T, pH and temperature not specified in the publication
0.000058
-
recombinant mutant F266S, pH and temperature not specified in the publication
0.00029
-
mutant N338I/A339T, pH 7.0, 22°C
0.024
-
mutant N338C, pH 7.0, 22°C
0.052
-
pH 7.0, 30°C, recombinant enzyme
4.46
-
pH 8.0, 30°C
0.079
-
pH 7.0, 30°C
0.0088
-
mutant N338A, pH 7.0, 22°C
0.069
-
mutant N338L, pH 7.0, 22°C
0.009
-
wild-type, pH 7.0, 22°C
0.053
-
mutant N338V, pH 7.0, 22°C
0.012
-
mutant A595G/F596L/L599F, 30°C, pH not specified in the publication
0.0352
-
temperature not specified in the publication, pH not specified in the publication
0.001
-
wild-type, 30°C, pH not specified in the publication
0.545
-
mutant F596L, 30°C, pH not specified in the publication
0.0825
-
mutant L596F, 30°C, pH not specified in the publication
0.643
-
mutant F596L, 30°C, pH not specified in the publication
0.0825
-
mutant A595G/F596L/L599F, 30°C, pH not specified in the publication
0.0352
-
wild-type, 30°C, pH not specified in the publication
pH 7.0, 30°C, recombinant enzyme
pH 7.0, 30°C
0.0003
-
pH 7.5, 23°C
0.012
-
pH 7.0, 30°C, recombinant enzyme
0.52
-
LaLIMS_RR, truncated protein
0.012
-
at pH 8.0, temperature not specified in the publication
0.186
-
presence of Mn2+, pH 7.5, 30°C
0.00034
-
presence of Mn2+, pH 6.5, 30°C
0.0007
-
pH 6.5
0.24
-
pH 7.1, 29°C
1300
-
pH and temperature not specified in the publication
0.036
-
mutant S485A
0.000588
-
mutant S487A
0.000005
-
mutant S488A
0.000052
-
mutant D484A
0.000034
-
wild-type
0.000281
-
pH 7.5
0.03
-
pH 7.5, 30°C, mutant enzyme D484A
0.000034
-
pH 7.5, 30°C, mutant enzyme S485A
0.000588
-
pH 7.5, 30°C, mutant enzyme S487A
0.000005
-
pH 7.5, 30°C, mutant enzyme S488A
0.000052
-
pH 7.5, 30°C, wild-type enzyme
0.000281
-
pH 7.5, 22°C, presence of Mg2+
0.13
-
pH 7.5, 22°C, presence of Mn2+
0.03
-
pH 6.5, 30°C
0.017
-

KM Value (186 results)

COMMENTARY
EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
LITERATURE
pH 7.0, 37°C, recombinant enzyme
0.0131
-
pH and temperature not specified in the publication
0.0131
-
at pH 7.5 and 30°C
0.008
-
pH 7.2, 20°C
0.012
-
0.042-0.056 mg/ml protein, isoenzyme I, Km values depend on protein concentration
0.036
-
0.042-0.056 mg/ml protein, isoenzyme II, Km values depend on protein concentration
0.039
-
at pH 7.5% and 30°C
0.063
-
C289F mutant enzyme at 55°C
7.5
-
C289S mutant enzyme at 55°C
6.4
-
C73F mutant enzyme at 45°C
4.9
-
C73F mutant enzyme at 55°C
7.3
-
C73S/C289S mutant enzyme at 55°C
5.6
-
fixed substrate isopentenyl diphosphate (0.05 mM), pH and temperature not specified in the publication, metal cofactor: Co2+
0.0243
-
fixed substrate isopentenyl diphosphate (0.05 mM), pH and temperature not specified in the publication, metal cofactor: Mg2+
0.0012
-
pH 7.2, 20°C
0.012
-
pH 7.9, 37°C
0.0098
-
wild-type enzyme at 45°C
5.8
-
wild-type enzyme at 55°C
8.4
-
with 1,3-dihydroxynaphthalene as cosubstrate, in 100 mM Na-TAPS (pH 8.5), at 30°C
0.0027
-
with flaviolin as cosubstrate, in 100 mM Na-TAPS (pH 8.5), at 30°C
0.0021
-
pH 7.5, 30°C, cosubstrate: 1,3-dihydroxynaphthalene
0.063
-
pH 7.5, 30°C, cosubstrate: 2-methoxy-3-methylflaviolin
0.098
-
pH 7.5, 30°C, cosubstrate: flaviolin
0.059
-
pH 7.5, 30°C, cosubstrate: 1,3-dihydroxynaphthalene
0.063
-
pH 7.5, 30°C, cosubstrate: 2-methoxy-3-methylflaviolin
0.098
-
pH 7.5, 30°C, cosubstrate: flaviolin
0.059
-
presence of prenyltransferase PT2, pH 7.0, 30°C
0.00618
-
truncated recombinant protein, pH 7.0, 30°C
0.0057
-
with phenyl(2,4,6-trihydroxyphenyl)methanone as cosubstrate, at pH 7.5 and 37°C
0.46
-
fixed substrate: isopentenyl diphosphate, enzyme EuFPS1, pH 7.0, 25°C
0.0097
-
fixed substrate: isopentenyl diphosphate, enzyme EuFPS2, pH 7.0, 25°C
0.011
-
GGPPS1
0.00363
-
GGPPS2
0.00236
-
pH 5.8, 55°C, wild-type enzyme
0.00072
-
pH 7.2, 20°C
0.012
-
pH 7.5, 37°C, recombinant enzyme, with isopentenyl diphosphate
0.0078
-
pH 7.7, 37°C, recombinant PvGGPPS
0.0019
-
pH 8.0, 70°C
0.0022
-
pH 8.0, 90°C
0.022
-
25°C, pH 7.5
0.036
-
pH 7.5, 35°C
0.0032
-
pH 7.6
0.001
-
-
0.0597
-
apparent Michaelis-Menten constant for peptide
0.027
-
mutant L84A/L85F
0.15
-
pH 7.5, 37°C
pH 7.9, 37°C
0.038
-
pH 7.9, 37°C, mutant enzyme L84A/L85F
0.15
-
pH and temperature not specified in the publication
0.0078
-
pH 7.4, 37°C
pH 7.9, 37°C
0.49
-
65°C
0.00175
-
pH 7.3, 37°C
0.005
-
pH 7.5, 37°C
pH 7.9, 37°C
0.49
-
wild-type, pH 7.5, 37°C
0.007
-
pH 7.6, 30°C, mutant enzyme D208E
0.0022
-
pH 7.6, 30°C, mutant enzyme D212E
0.0365
-
pH 7.6, 30°C, wild-type enzyme
0.0295
-
pH 7.8, 37°C
0.0138
-
recombinant enzyme, pH 7.0-7.5, 45°C
0.0138
-
pH 7.0, 30°C
0.0558
-
pH 7.0, 32°C
0.0585
-
pH 7.5, 32°C
0.0895
-
pH 8.5, 37°C, Met44-truncated mutant
0.03
-
pH 8.5, 37°C, Ser35 truncated mutant
0.029
-
pH 8.5, 37°C, wild-type enzyme
0.021
-
pH not specified in the publication, temperature not specified in the publication
0.00014
-
-
0.006
-
20 mM MgCl2, 0.2 mM MnCl2, 0.2 mM NaWO4, and 0.1 mM NaF, pH not specified in the publication, at 30°C
0.0009
-
pH 7.5, 38°C, recombinant His-tagged enzyme
0.0736
-
accession Columbia, 30°C, pH not specified in the publication
0.0067
-
mutant L596F, 30°C, pH not specified in the publication
0.0153
-
pH 6.5, 31°C
0.0048
-
pH 7.4, 30°C, proteins from both susceptible and resistant plants have similar kinetic parameters
0.00688
-
pH 7.8, 32°C
0.0037
-
recombinant His-tagged enzyme, pH 7.2, temperature not specified in the publication
0.00369
-
wild-type, 30°C, pH not specified in the publication
0.0158
-
mutant N338A, pH 7.0, 22°C
0.0119
-
mutant N338C, pH 7.0, 22°C
0.201
-
mutant N338I, pH 7.0, 22°C
0.0566
-
mutant N338I/A339T, pH 7.0, 22°C
0.136
-
mutant N338I/A339T/G447S, pH 7.0, 22°C
0.0955
-
mutant N338I/A339T/G447S/I449P/P450T, pH 7.0, 22°C
0.0129
-
mutant N338L, pH 7.0, 22°C
0.0265
-
mutant N338S, pH 7.0, 22°C
0.0144
-
mutant N338V, pH 7.0, 22°C
0.055
-
pH 6.3, 30°C
0.0011
-
pH 7.0, 30°C
0.0057
-
pH 7.0, 30°C, recombinant enzyme
0.0177
-
pH 7.1, 31°C
0.007
-
pH 8.0, 30°C
0.00017
-
recombinant mutant F266S, pH and temperature not specified in the publication
0.00012
-
recombinant mutant F266T, pH and temperature not specified in the publication
0.00004
-
recombinant mutant F266V, pH and temperature not specified in the publication
0.00004
-
recombinant wild-type enzyme, pH and temperature not specified in the publication
0.00019
-
temperature not specified in the publication, pH not specified in the publication
0.0002
-
wild-type, pH 7.0, 22°C
0.0654
-
mutant A595G/F596L/L599F, 30°C, pH not specified in the publication
0.0202
-
mutant F596L, 30°C, pH not specified in the publication
0.0316
-
pH 7.0, 32°C
0.004
-
temperature not specified in the publication, pH not specified in the publication
0.0002
-
wild-type, 30°C, pH not specified in the publication
0.0357
-
pH 7.0, 30°C
0.0019
-
pH 7.1, 31°C
0.0074
-
mutant A595G/F596L/L599F, 30°C, pH not specified in the publication
0.0202
-
mutant F596L, 30°C, pH not specified in the publication
0.0316
-
mutant L596F, 30°C, pH not specified in the publication
0.0153
-
pH 6.5, 30°C
pH 7.0, 30°C
0.0474
-
wild-type, 30°C, pH not specified in the publication
pH 6.6, 30°C
0.014
-
pH 6.8, 30°C
pH 7.0, 30°C
0.0027
-
pH 7.1, 31°C
0.0074
-
pH 7.0, 30°C, recombinant enzyme
pH 7.0, 30°C
0.0028
-
30°C, pH not specified in the publication
0.793
-
pH 6.5, 30°C
0.003
-
pH 6.5, 31°C
0.0014
-
pH 6.8, 31°C
0.0016
-
pH 7.2, 30°C
0.0031
-
pH 7.8, temperature not specified in the publication
0.006
-
pH and temperature not specified in the publication
0.0014
-
30°C, pH not specified in the publication
0.793
-
pH 6.5, 30°C
0.003
-
pH 7.0, 30°C
0.0031
-
pH 7.0, 31°C
0.0025
-
pH 7.2, 30°C
0.0031
-
pH 7.8, temperature not specified in the publication
0.006
-
pH 5.8, 31°C
0.001
-
pH 6.5, 30°C
0.0021
-
pH 6.5, 31°C
0.047
-
pH 7.5, 23°C
0.0474
-
pH 6.8, 31°C
0.0016
-
pH 7.0, 30°C, recombinant enzyme
0.00825
-
at pH 8.0, temperature not specified in the publication
0.0131
-
LaLIMS_RR, truncated protein
0.0474
-
pH 7.0, 30°C
0.0474
-
presence of Mn2+, pH 6.5, 30°C
0.0169
-
presence of Mn2+, pH 7.5, 30°C
0.0282
-
25 mM Mg2+
pH 6.6, 30°C
0.018
-
pH 7.4, 20°C
0.0009
-
isoenzyme QH1, pH 7.0, 30°C
0.064
-
pH 6.5
0.025
-
pH 7.1, 29°C
0.0285
-
pH and temperature not specified in the publication
0.0092
-
pH 7.5
0.0028
-
pH 7.5, 22°C, presence of Mg2+
0.0019
-
32°C
0.0078
-
pH 6.5, 30°C
0.00655
-
recombinant enzyme, in the presence of 0.05 mM Mn2+, pH and temperature not specified in the publication
0.0011
-
pH and temperature not specified in the publication
0.0023
-

Ki Value (10 results)

COMMENTARY
EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
LITERATURE
fixed substrate isopentenyl diphosphate (0.05 mM), pH and temperature not specified in the publication, metal cofactor: Mg2+
0.322
-
-
0.116
-
at pH 7.5, temperature not specified in the publication
0.00055
-
liver mevalonate kinase
0.002
-
pH 7.0, 25°C, recombinant mevalonate kinase
0.116
-
pH 7.0, 30°C
-
0.1
-

IC50 Value (1 result)

COMMENTARY
EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
LITERATURE
-
0.005
-

References & Links

Links to other databases for geranyl diphosphate

ChEBI
PubChem
-
PubChem