print visible entries

print all entries

Ligand 1-octyne

Basic Ligand Information

Molecular Structure

close all tables

open all tables

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (1 result)

top print hide

Show Substrate (1 entry)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.14.15.3

2 1-octyne + 2 NADH + 2 H+ + 2 O2 = 1-octanoic acid + 7-octynoic acid + 2 NAD+ + 2 H2O

744267

-

Inhibitor in Enzyme-catalyzed Reactions (3 results)

top print hide

Show Inhibitors (3 entries)

EC NUMBER

COMMENTARY

LITERATURE

ENZYME 3D STRUCTURE

1.1.1.400

-

737503

-

1.14.15.3

acts as a mechanism-based inhibitor of AlkB

724025

-

1.14.15.3

irreversible inhibition, oxidation product hexylketene or its equivalent, covalently binds to AlkB

744267

-

1.14.15.3

2 entries

Enzyme Kinetic Parameters

References & Links

Literature References (3)

top print hide

Show Reference (3 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

724025

22941083

Characterization and two-dimensional crystallization of membrane component AlkB of the medium-chain alkane hydroxylase system from Pseudomonas putida GPo1

2012

Alonso, H.; Roujeinikova, A.

Appl. Environ. Microbiol.

78

7946-7953

737503

25576605

Metabolism of 2-methylpropene (isobutylene) by the aerobic bacterium Mycobacterium sp. strain ELW1

2015

Kottegoda, S.; Waligora, E.; Hyman, M.

Appl. Environ. Microbiol.

81

1966-1976

744267

24646189

Structural and mechanistic insight into alkane hydroxylation by Pseudomonas putida AlkB

2014

Alonso, H.; Kleifeld, O.; Yeheskel, A.; Ong, P.C.; Liu, Y.C.; Stok, J.E.; De Voss, J.J.; Roujeinikova, A.

Biochem. J.

460

283-293

Links to other databases for 1-octyne

top print hide

Show Links (1 entry)

ChEBI

PubChem

-