Ligand Leu-Gly

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Basic Ligand Information

Molecular Structure
Picture of Leu-Gly (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C8H16N2O3
Leu-Gly
LESXFEZIFXFIQR-LURJTMIESA-N
Synonyms:
L-Leu-Gly, L-Leu-Gly[side 2], L-leucyl-glycine, L-leucylglycine, leucylglycine

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (19 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
Leu-Gly + H2O = Leu + Gly
show the reaction diagram
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Leu-Gly + H2O = Leu + Gly
show the reaction diagram
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Leu-Gly + H2O = Leu + Gly
show the reaction diagram
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Leu-Gly + H2O = Leu + Gly
show the reaction diagram
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Leu-Gly + H2O = L-Leu + Gly
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L-Leu-Gly + H2O = L-Leu + Gly
show the reaction diagram
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Leu-Gly + H2O = Leu + Gly
show the reaction diagram
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Leu-Gly + H2O = Leu + Gly
show the reaction diagram
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Leu-Gly + H2O = Leu + Gly
show the reaction diagram
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benzyloxycarbonyl-Glu-methyl ester + Leu-Gly = benzyloxycarbonyl-Glu-Leu-Gly + methanol
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L-Leu-Gly + H2O = ?
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Product in Enzyme-catalyzed Reactions (12 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
Asp-Leu-Gly + H2O = Asp + Leu-Gly
show the reaction diagram
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Met-Leu-Gly + H2O = Met + Leu-Gly
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Asp-Leu-Gly + H2O = Asp + Leu-Gly
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Leu-Gly-2-naphthylamide + H2O = Leu-Gly + 2-naphthylamine
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formyl-Met-Leu-Gly + H2O = formyl-Met + Leu-Gly
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Leu-Gly-NH2 + H2O = Leu-Gly + NH3
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ATP + L-leucine + glycine = ADP + phosphate + L-leucyl-glycine
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ATP + H2O + L-Leu-Gly-[dipeptide-binding protein][side 1] = ADP + phosphate + L-Leu-Gly[side 2] + [dipeptide-binding protein][side 1]
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Inhibitor in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
inhibits the activity of the Mn2+-Zn2+-enzyme with substrate Cys-Gly competitively
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competitive
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (13 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
6.5
-
pH 7.5, 30C
6630
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pH 7.5, 37C

KM Value (21 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.95
-
pH 7.5, 30C
13.5
-
pH 7.5, 37C
0.21
-
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Ki Value (2 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.65
-
Z2+-Zn2+-enzyme, versus substrate Cys-Gly
0.19
-
-

References & Links

Links to other databases for Leu-Gly

ChEBI
PubChem
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PubChem