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Ligand 7-aminocephalosporanic acid

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Basic Ligand Information

Molecular Structure
Picture of 7-aminocephalosporanic acid (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C10H12N2O5S
7-aminocephalosporanic acid
HSHGZXNAXBPPDL-HZGVNTEJSA-N
Synonyms:
(6R,7R)-3-acetoxymethyl-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, (6R,7R)-3-[(acetyloxy)methyl]-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate, (6R,7R)-3-[(acetyloxy)methyl]-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, (7R)-7-aminocephalosporanate, 7-amino-cephalosporanic acid, 7-aminocephalosporanate, 7-amino cephalosporanic acid, 7beta-aminocephalosporanic acid

Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Substrate in Enzyme-catalyzed Reactions (18 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
7-aminocephalosporanic acid + H2O = ?
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (32 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
cephalosporin C + H2O + O2 = 7-aminocephalosporanic acid + ? + H2O2
show the reaction diagram
-
-
cephalosporin C + H2O = 7-aminocephalosporanic acid + ?
show the reaction diagram
-
-

Inhibitor in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (13 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.46
-
pH and temperature not specified in the publication

KM Value (19 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
-999
-
estimated value: 9.43 mg/ml, pH 7.6, 34°C, Vmax: 7.65 U/ml

Ki Value (5 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

References & Links

Links to other databases for 7-aminocephalosporanic acid

ChEBI
PubChem
ChEBI
PubChem