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Catalytic and structural properties of the dihydrolipoyl transacylase component of bovine branched-chain alpha-keto acid dehydrogenase
1984
Chuang, D.T.; Hu, C.C.; Ku, L.S.; Niu, W.L.; Myers, D.E.; Cox, R.P.
J. Biol. Chem.
259
9277-9284
Subunit structure of the dihydrolipoyl transacylase component of branched-chain alpha-keto acid dehydrogenase complex from bovine liver. Characterization of the inner transacylase core
1985
Chuang, D.T.; Hu, C.W.; Ku, L.S.; Markovitz, P.J.; Cox, R.P.
J. Biol. Chem.
260
13779-13786
Subunit structure of the dihydrolipoyl transacylase component of branched-chain alpha-keto acid dehydrogenase complex from bovine liver. Mapping of the lipoyl-bearing domain by limited proteolysis
1986
Hu, C.W.; Griffin, T.A.; Lau, K.S.; Cox, R.P.; Chuang, D.T.
J. Biol. Chem.
261
343-349
Maple syrup urine disease: domain structure, mutations and exon skipping in the dihydrolipoyl transacylase (E2) component of the branched-chain alpha-keto acid dehydrogenase complex
1991
Chuang, D.T.; Fisher, C.W.; Lau, K.S.; Griffin, T.A.; Wynn, R.M.; Cox, R.P.
Mol. Biol. Med.
8
49-63
Structure of the gene encoding dihydrolipoyl transacylase (E2) component of human branched chain alpha-keto acid dehydrogenase complex and characterization of an E2 pseudogene
1992
Lau, K.S.; Herring, W.J.; Chuang, J.L.; McKean, M.; Danner, D.J.; Cox, R.P.; Chuang, D.T.
J. Biol. Chem.
267
24090-24096
The complete cDNA sequence for dihydrolipoyl transacylase (E2) of human branched-chain alpha-keto acid dehydrogenase complex
1992
Lau, K.S.; Chuang, J.L.; Herring, W.J.; Danner, D.J.; Cox, R.P.; Chuang, D.T.
Biochim. Biophys. Acta
1132
319-321
Epitope mapping of the branched chain alpha-ketoacid dehydrogenase dihydrolipoyl transacylase (BCKD-E2) protein that reacts with sera from patients with idiopathic dilated cardiomyopathy
1994
Ansari, A.A.; Neckelmann, N.; Villinger, F.; Leung, P.; Danner, D.J.; Brar, S.S.; Zhao, S.; Gravanis, M.B.; Mayne, A.; Gershwin, M.E.
J. Immunol.
153
4754-4765
Swinging arms and swinging domains in multifunctional emzymes: catalytic machines for multistep reactions
2000
Perham, R.N.
Annu. Rev. Biochem.
69
961-1004
Production of recombinant mammalian holo-E2 and E3 and reconstitution of functional branched-chain alpha-keto acid dehydrogenase complex with recombinant E1
2000
Chuang, J.L.; Davie, J.R.; Wynn, R.M.; Chuang, D.T.
Methods Enzymol.
324
192-200
Characterization of rainbow trout branched-chain alpha-keto acid dehydrogenase complex: inter-domain segments of the E2 component affect the overall activity
2002
Hakozaki, M.; Ono, K.; Suzuki, T.; Hata, H.; Mori, T.; Kochi, H.
Comp. Biochem. Physiol. B Biochem. Mol. Biol.
132
433-442
Invitro reconstitution of the 24-meric E2 inner core of bovine mitochondrial branched-chain alpha-keto acid dehydrogenase complex: requirements for chaperonins GroEL and GroES
1994
Wynn, R.M.; Davie, J.R.; Zhi, W.; Cox, R.P.; Chuang, D.T.
Biochemistry
33
8962-8968
Expression and purification of the dihydrolipoamide acetyltransferase and dihydrolipoamide dehydrogenase subunits of the Escherichia coli pyruvate dehydrogenase multienzyme complex: a mass spectrometric assay for reductive acetylation of dihydrolipoamide acetyltransferase
2003
Wei, W.; Li, H.; Nemeria, N.; Jordan, F.
Protein Expr. Purif.
28
140-150
Insight to the interaction of the dihydrolipoamide acetyltransferase (E2) core with the peripheral components in the Escherichia coli pyruvate dehydrogenase complex via multifaceted structural approaches
2013
Chandrasekhar, K.; Wang, J.; Arjunan, P.; Sax, M.; Park, Y.H.; Nemeria, N.S.; Kumaran, S.; Song, J.; Jordan, F.; Furey, W.
J. Biol. Chem.
288
15402-15417
Identification of a novel mitochondrial interacting protein of C1QBP using subcellular fractionation coupled with CoIP-MS
2016
Chen, R.; Xiao, M.; Gao, H.; Chen, Y.; Li, Y.; Liu, Y.; Zhang, N.
Anal. Bioanal. Chem.
408
1557-1564
Loss of dihydrolipoyl succinyltransferase (DLST) leads to reduced resting heart rate in the zebrafish
2015
Kessler, M.; Berger, I.M.; Just, S.; Rottbauer, W.
Basic Res. Cardiol.
110
14
Structure and function of the catalytic domain of the dihydrolipoyl acetyltransferase component in Escherichia coli pyruvate dehydrogenase complex
2014
Wang, J.; Nemeria, N.S.; Chandrasekhar, K.; Kumaran, S.; Arjunan, P.; Reynolds, S.; Calero, G.; Brukh, R.; Kakalis, L.; Furey, W.; Jordan, F.
J. Biol. Chem.
289
15215-15230
Novel binding motif and new flexibility revealed by structural analyses of a pyruvate dehydrogenase-dihydrolipoyl acetyltransferase subcomplex from the Escherichia coli pyruvate dehydrogenase multienzyme complex
2014
Arjunan, P.; Wang, J.; Nemeria, N.S.; Reynolds, S.; Brown, I.; Chandrasekhar, K.; Calero, G.; Jordan, F.; Furey, W.
J. Biol. Chem.
289
30161-30176
Structure of the dihydrolipoamide succinyltransferase catalytic domain from Escherichia coli in a novel crystal form a tale of a common protein crystallization contaminant
2019
Andi, B.; Soares, A.S.; Shi, W.; Fuchs, M.R.; McSweeney, S.; Liu, Q.
Acta Crystallogr. Sect. F
75
616-624
Inhibition of microRNA-146a and overexpression of its target dihydrolipoyl succinyltransferase protect against pressure overload-induced cardiac hypertrophy and dysfunction
2017
Heggermont, W.A.; Papageorgiou, A.P.; Quaegebeur, A.; Deckx, S.; Carai, P.; Verhesen, W.; Eelen, G.; Schoors, S.; van Leeuwen, R.; Alekseev, S.; Elzenaar, I.; Vinckier, S.; Pokreisz, P.; Walravens, A.S.; Gijsbers, R.; Van Den Haute, C.; Nickel, A.; Schroen, B.; van Bilsen, M.; Janssens, S.; Maack, C.; Pinto, Y.; Carmeliet, P.; Heymans, S.
Circulation
136
747-761
Catalysis of transthiolacylation in the active centers of dihydrolipoamide acyltransacetylase components of 2-oxo acid dehydrogenase complexes
2018
Chakraborty, J.; Nemeria, N.S.; Farinas, E.; Jordan, F.
FEBS Open Bio
8
880-896
Sulfone-based probes unraveled dihydrolipoamide S-succinyltransferase as an unprecedented target in phytopathogens
2019
Chen, B.; Long, Q.; Zhao, Y.; Wu, Y.; Ge, S.; Wang, P.; Yang, C.G.; Chi, Y.; Song, B.; Yang, S.
J. Agric. Food Chem.
67
6962-6969
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