Ligand enzyme N6-(dihydrolipoyl)lysine

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Basic Ligand Information

Molecular Structure
Picture of enzyme N6-(dihydrolipoyl)lysine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C37H60N8O12S3
enzyme N6-(dihydrolipoyl)lysine
DRJQQABNSSYRJL-SYCOSFMXSA-N
Synonyms:
protein-dihydrolipoyllysine, protein 6-N-(dihydrolipoyl)lysine, protein N6-(dihydrolipoyl)lysine, [protein]-dihydrolipoyllysine

Show all pahtways known for Show all BRENDA pathways known for enzyme N6-(dihydrolipoyl)lysine

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
acetyl-CoA + enzyme N6-(dihydrolipoyl)lysine = CoA + enzyme N6-(S-acetyldihydrolipoyl)lysine
show the reaction diagram
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2-methylpropanoyl-CoA + enzyme N6-(dihydrolipoyl)lysine = CoA + enzyme N6-(S-[2-methylpropanoyl]dihydrolipoyl)lysine
show the reaction diagram
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succinyl-CoA + enzyme N6-(dihydrolipoyl)lysine = CoA + enzyme N6-(S-succinyldihydrolipoyl)lysine
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
protein N6-(lipoyl)lysine + NADH + H+ = protein N6-(dihydrolipoyl)lysine + NAD+
show the reaction diagram
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[protein]-S8-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
acetyl-CoA + enzyme N6-(dihydrolipoyl)lysine = CoA + enzyme N6-(S-acetyldihydrolipoyl)lysine
show the reaction diagram
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2-methylpropanoyl-CoA + enzyme N6-(dihydrolipoyl)lysine = CoA + enzyme N6-(S-[2-methylpropanoyl]dihydrolipoyl)lysine
show the reaction diagram
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succinyl-CoA + enzyme N6-(dihydrolipoyl)lysine = CoA + enzyme N6-(S-succinyldihydrolipoyl)lysine
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
protein N6-(lipoyl)lysine + NADH + H+ = protein N6-(dihydrolipoyl)lysine + NAD+
show the reaction diagram
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[protein]-S8-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3
show the reaction diagram
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CoA + enzyme N6-(S-acetyldihydrolipoyl)lysine = acetyl-CoA + enzyme N6-(dihydrolipoyl)lysine
show the reaction diagram
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Enzyme Kinetic Parameters

References & Links

Links to other databases for enzyme N6-(dihydrolipoyl)lysine

ChEBI
PubChem
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PubChem