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BRENDA support

Ligand 2-mercaptopurine

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Basic Ligand Information

Molecular Structure
Picture of 2-mercaptopurine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C5H4N4S
2-mercaptopurine
HDBQZGJWHMCXIL-UHFFFAOYSA-N

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-mercaptopurine + H2O + O2 = 8-hydroxy-2-mercaptopurine + H2O2
show the reaction diagram
-
thymidine + 2-mercaptopurine = more
show the reaction diagram
-

Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
1.98
-
25°C

KM Value (1 result)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.00088
-
25°C

References & Links

Links to other databases for 2-mercaptopurine

ChEBI
PubChem
-
PubChem