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Ligand dTDP-galactose Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Basic Ligand Information Molecular Structure
C1 6 H2 6 N2 O1 6 P2
dTDP-galactose
YSYKRGRSMLTJNL-OAOVJFGZSA-N
dTDP-D-galactose, dTDPgalactose, TDP-D-galactose, TDP-galactose, TDPgalactose
Roles as Enzyme Ligand
Product in Enzyme-catalyzed Reactions (7 results)
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TDP-glucose + alpha-D-galactose 1-phosphate = alpha-D-glucose 1-phosphate + TDP-galactose
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dTTP + alpha-D-galactose 1-phosphate = dTDP-galactose + diphosphate
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dTTP + alpha-D-galactose-1-phosphate = dTDP-galactose + diphosphate
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dTTP + alpha-D-galactose 1-phosphate = dTDPgalactose + ?
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D-galactose 1-phosphate + dTTP = dTDP-D-galactose + diphosphate
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D-galactose 1-phosphate + TTP = TDP-D-galactose + diphosphate
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TDP-D-glucose = TDP-D-galactose
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Inhibitor in Enzyme-catalyzed Reactions (1 result)
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Enzyme Kinetic Parameters
Ki Value (1 result)
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0.097
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pH 7.5, 37°C, wild-type enzyme
References & Links Literature References (4)
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UDP-galactose-4-epimerase
1975
Gabrial, O.; Kalckar, H.M.; Darrow, R.A.
ubunit enzymes: biochemistry and function
(Ebner, K. B., ed.)
2
85-135
4-Uloses as intermediates in enzyme-nicotinamide adenine dinucleotide-mediated oxidoreductase mechanisms
1973
Adair, W.L.; Gabriel, O.; Ullrey, D.; Kalckar, H.M.
J. Biol. Chem.
248
4635-4639
Thymidine triphosphate: alpha-D-galactose 1-phosphate thymidylyltransferase from Streptococcus faecalis grown on D-galactose
1963
Pazur, J.H.; Anderson, J.S.
J. Biol. Chem.
238
3155-3160
Probing catalysis by Escherichia coli dTDP-glucose-4,6-dehydratase: identification and preliminary characterization of functional amino acid residues at the active site
2001
Hegeman, A.D.; Gross, J.W.; Frey, P.A.
Biochemistry
40
6598-6610
Links to other databases for dTDP-galactose
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