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Ligand stevioside

Basic Ligand Information

Molecular Structure

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Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (8 results)

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Show Substrate (8 entries)

EC NUMBER

LITERATURE

REACTION DIAGRAM

REACTION

ENZYME 3D STRUCTURE

2.4.1.140

736133

stevioside + sucrose = ?

-

2.4.1.19

488848, 488854

starch + stevioside = glycosyl stevioside

-

2.4.1.19

702819

stevioside + beta-cyclodextrin = 4'-O-alpha-D-glycosyl stevioside + 4''-O-alpha-D-maltosyl stevioside + ?

-

2.4.1.19

685718

stevioside + maltodextrin = ?

-

2.4.1.19

685718

stevioside + starch = ?

-

2.4.1.19

4 entries

2.4.1.5

753456

sucrose + stevioside = 13-O-beta-sophorosyl-19-O-beta-isomaltosyl-steviol + 13-O-(beta-(1->6) glucosyl)-beta-glucosylsophorosyl-19-O-beta-isomaltosyl-steviol + 13-O-beta-sophorosyl-19-O-beta-isomaltotriosyl-steviol

-

3.2.1.21

731732

stevioside + H2O = rubusoside + D-glucose

-

3.2.1.B26

744812

stevioside + H2O = steviol + D-glucose

-

Activator in Enzyme-catalyzed Reactions (1 result)

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Show Activating Compound (1 entry)

COMMENTARY

EC NUMBER

LITERATURE

ENZYME 3D STRUCTURE

0.001 mM, in the presence of 16.7 mM glucose

6.4.1.2

671236

-

Inhibitor in Enzyme-catalyzed Reactions (1 result)

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Show Inhibitors (1 entry)

COMMENTARY

EC NUMBER

LITERATURE

ENZYME 3D STRUCTURE

-

2.5.1.54

738155

-

Enzyme Kinetic Parameters

k_cat Value (Turnover Number) (1 result)

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Show Turnover Number (1 entry)

COMMENTARY

EC NUMBER

LITERATURE

TURNOVER NUMBER [1/S]

TURNOVER NUMBER MAXIMUM [1/S]

at pH 6.0 and 80°C

3.2.1.B26

744812

1.62

-

K_M Value (1 result)

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Show KM Value (1 entry)

COMMENTARY

EC NUMBER

KM VALUE [MM]

KM VALUE MAXIMUM [MM]

LITERATURE

at pH 6.0 and 80°C

3.2.1.B26

17.21

-

744812

References & Links

Literature References (10)

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Show Reference (10 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

488848

7763423

Enzymatic synthesis of a novel trisaccharide, glucosyl lactoside

1993

Shibuya, T.; Miwa, Y.; Nakano, M.; Yamauchi, T.; Chaen, H.; Sakai, S.; Kurimoto, M.

Biosci. Biotechnol. Biochem.

57

56-60

488854

-

Characteristics of transglycosylation reaction of cyclodextrin glucanotransferase in the heterogeneous enzyme reaction system using extrusion starch as a glucosyl donor

1998

Park, D.C.; Kim, T.K.; Lee, Y.H.

Enzyme Microb. Technol.

22

217-222

671236

17341549

Stevioside improves pancreatic beta-cell function during glucotoxicity via regulation of acetyl-CoA carboxylase

2007

Chen, J.; Jeppesen, P.B.; Nordentoft, I.; Hermansen, K.

Am. J. Physiol. Endocrinol. Metab.

292

E1906-E1916

685718

-

Catalytic properties of beta -cyclodextrin glucanotransferase from alkalophilic Bacillus sp. BL-12 and intermolecular transglycosylation of stevioside

2007

Jung, S.; Kim, T.; Lee, K.; Lee, Y.

Biotechnol. Bioprocess Eng.

12

207-212

702819

19466564

Simple and efficient enzymatic transglycosylation of stevioside by beta-cyclodextrin glucanotransferase from Bacillus firmus

2009

Jaitak, V.; Kaul, V.K.; Bandna, V.K.; Kumar, N.; Singh, B.; Savergave, L.S.; Jogdand, V.V.; Nene, S.

Biotechnol. Lett.

31

1415-1420

731732

25152415

Production of rubusoside from stevioside by using a thermostable lactase from Thermus thermophilus and solubility enhancement of liquiritin and teniposide

2014

Nguyen, T.T.; Jung, S.J.; Kang, H.K.; Kim, Y.M.; Moon, Y.H.; Kim, M.; Kim, D.

Enzyme Microb. Technol.

64-65

38-43

736133

24176308

Biotransformation of stevioside by Leuconostoc citreum SK24.002 alternansucrase acceptor reaction

2014

Musa, A.; Miao, M.; Zhang, T.; Jiang, B.

Food Chem.

146

23-29

738155

26491981

Inhibition of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from Mycobacterium tuberculosis: in silico screening and in vitro validation

2015

Nirmal, C.R.; Rao, R.; Hopper, W.

Eur. J. Med. Chem.

105

182-193

744812

27702476

Production of steviol from steviol glucosides using beta-glycosidase from Sulfolobus solfataricus

2016

Nguyen, T.T.; Kim, S.B.; Kim, N.M.; Kang, C.; Chung, B.; Park, J.S.; Kim, D.

Enzyme Microb. Technol.

93-94

157-165

753456

31731958

Synthesis and characterization of stevioside having low degree polymerized glucosides using dextransucrase and dextranase

2020

Son, G.; Nguyen, T.T.H.; Park, B.; Kwak, S.; Jin, J.; Kim, Y.M.; Moon, Y.H.; Park, S.; Kim, S.B.; Kim, D.

Enzyme Microb. Technol.

132

109412

Links to other databases for stevioside

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Show Links (1 entry)

ChEBI

PubChem

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