Ligand pentafluorobenzaldehyde
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Basic Ligand Information
Molecular Structure

C7HF5O
pentafluorobenzaldehyde
QJXCFMJTJYCLFG-UHFFFAOYSA-N
2,3,4,5,6-pentafluorobenzaldehyde, 2-pentafluorobenzaldehyde
Roles as Enzyme Ligand
Substrate in Enzyme-catalyzed Reactions (3 results)
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D-alanine + pentafluorobenzaldehyde + H2O = (2S,3S)-2-amino-3-hydroxy-2-methyl-3-(pentafluorophenyl)propanoic acid + (2S,3R)-2-amino-3-hydroxy-2-methyl-3-(pentafluorophenyl)propanoic acid
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D-serine + pentafluorobenzaldehyde + H2O = (2S,3S)-2-amino-3-hydroxy-2-(hydroxymethyl)-3-(pentafluorophenyl)propanoic acid + (2S,3R)-2-amino-3-hydroxy-2-(hydroxymethyl)-3-(pentafluorophenyl)propanoic acid
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glycine + pentafluorobenzaldehyde + H2O = (2S,3S)-2-amino-3-hydroxy-3-(pentafluorophenyl)propanoic acid + (2S,3R)-2-amino-3-hydroxy-3-(pentafluorophenyl)propanoic acid
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Product in Enzyme-catalyzed Reactions (1 result)
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2,3,4,5,6-pentafluorobenzyl alcohol + NAD+ = 2,3,4,5,6-pentafluorobenzaldehyde + NADH + H+
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Inhibitor in Enzyme-catalyzed Reactions (2 results)
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0.1 mM, 44% inhibition, benzaldehyde dehydrogenase II
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Enzyme Kinetic Parameters
References & Links
Literature References (2)
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Benzyl alcohol dehydrogenase and benzaldehyde dehydrogenase II from Acinetobacter calcoaceticus. Substrate specificities and inhibition studies
1988
MacKintosh, R.W.; Fewson, C.A.
Biochem. J.
255
653-661
Engineered L-serine hydroxymethyltransferase from Streptococcus thermophilus for the synthesis of alpha,alpha-dialkyl-alpha-amino acids
2015
Hernandez, K.; Zelen, I.; Petrillo, G.; Uson, I.; Wandtke, C.M.; Bujons, J.; Joglar, J.; Parella, T.; Clapes, P.
Angew. Chem. Int. Ed. Engl.
54
3013-3017
Links to other databases for pentafluorobenzaldehyde