Ligand cis-benzene dihydrodiol

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Basic Ligand Information

Molecular Structure
Picture of cis-benzene dihydrodiol (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C6H8O2
cis-benzene dihydrodiol
YDRSQRPHLBEPTP-OLQVQODUSA-N
Synonyms:
(1R,2S)-cis-cyclohexa-3,5-diene-1,2-diol, 3,5-cyclohexadiene-1,2-diol, benzene cis-dihydrodiol, benzene dihydrodiol, benzenedihydrodiol, benzene diohydrodiol, cis-1,2-dihydrobenzene-1,2 diol, cis-1,2-dihydrobenzene-1,2-diol, cis-1,2-dihydroxy-3,5-cyclohexadiene, cis-1,3-cyclohexadiene-5,6-diol, cis-benzene-1,2-dihydrodiol, cis-benzeneglycol, cis-benzene glycol, cis-cyclohexa-3,5-diene-1,2-diol

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

In Vivo Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
benzene + NADH + O2 = benzene dihydrodiol + NAD+
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (23 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
benzene dihydrodiol + NAD(P)+ = o-benzoquinone + NAD(P)H
show the reaction diagram
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cis-benzene dihydrodiol + NAD+ = ? + NADH + H+
show the reaction diagram
-
cis-1,2-dihydroxy-3,5-cyclohexadiene + NADP+ = catechol + NADPH
show the reaction diagram
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benzenedihydrodiol + NAD(P)+ = ? + NAD(P)+
show the reaction diagram
-
benzenedihydrodiol + NADP+ = ?
show the reaction diagram
-
benzenedihydrodiol + NADP+ = ?
show the reaction diagram
-
cis-benzene dihydrodiol + NAD+ = ?
show the reaction diagram
-
benzene dihydrodiol + NADP+ = catechol + NADPH
show the reaction diagram
-
benzene dihydrodiol + NADP+ = o-benzoquinone + NADPH
show the reaction diagram
-
cis-cyclohexa-3,5-diene-1,2-diol + tert-butyl hydroperoxide = (1R,2S,3S,4S)-cyclohex-5-ene-1,2,3,4-tetrol + ?
show the reaction diagram
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benzene cis-dihydrodiol + NAD+ = catechol + NADH + H+
show the reaction diagram
-
cis-1,2-dihydrobenzene-1,2-diol + NAD(P)+ = catechol + NAD(P)H
show the reaction diagram
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cis-benzene dihydrodiol + NAD+ = dihydroxybenzene + NADH
show the reaction diagram
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cis-1,3-cyclohexadiene-5,6-diol + NAD+ = ?
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (9 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
benzene + NADH + O2 = H2O2 + cis-benzene-1,2-dihydrodiol + NAD+
show the reaction diagram
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benzoate + NADH + O2 = 3,5-cyclohexadiene-1,2-diol + NAD+ + CO2
show the reaction diagram
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (13 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.025
-
pH 7.4, 25C, recombinant enzyme
0.433
-
recombinant enzyme
27.8
-
pH 8.0, 30C

KM Value (30 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
1.99
-
cofactor NADP+
1.75
-
cosubstrate NAD+
0.0097
-
pH 7.4, 25C, recombinant enzyme
0.056
-
recombinant enzyme
0.78
-
pH 8.0, 30C
0.286
-
-
0.05
-
strain biotype A grown on benzene

References & Links

Links to other databases for cis-benzene dihydrodiol

ChEBI
PubChem
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PubChem