Ligand 2-hydroxy-5-methyl-6-oxohexa-2,4-dienoate

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Basic Ligand Information

Molecular Structure
Picture of 2-hydroxy-5-methyl-6-oxohexa-2,4-dienoate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C7H8O4
2-hydroxy-5-methyl-6-oxohexa-2,4-dienoate
ADNFTGVUUFRKSK-JGJYBARTSA-N
Synonyms:
2-hydroxy-5-methyl-muconic-6-semialdehyde, 2-hydroxy-5-methyl-muconic semialdehyde, 2-hydroxy-5-methylmuconic semialdehyde

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-hydroxy-5-methylmuconic semialdehyde + H2O = ?
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-hydroxy-5-methyl-6-oxohexa-2,4-dienoate + NAD+ + H2O = (2E,4Z)-2-hydroxy-5-methylhexa-2,4-diendioate + NADH + H+
show the reaction diagram
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2-hydroxy-5-methylmuconic semialdehyde + H2O = ?
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
4-methylcatechol + O2 = 2-hydroxy-5-methyl-6-oxohexa-2,4-dienoate + H+
show the reaction diagram
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (2 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
99300
-
pH 8.5, 25°C
16
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-

KM Value (4 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.0093
-
in 100 mM Tris-HCl, pH 8.5, at 25°C
0.0074
-
-

References & Links

Links to other databases for 2-hydroxy-5-methyl-6-oxohexa-2,4-dienoate

ChEBI
PubChem
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PubChem