Ligand N-oleoyl-phytoceramide
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Basic Ligand Information
Molecular Structure

C36H71NO3
N-oleoyl-phytoceramide
MJQIARGPQMNBGT-WWUCIAQXSA-N
N-(oleoyl)-dihydrosphingosine, N-oleoylsphinganine
Roles as Enzyme Ligand
Substrate in Enzyme-catalyzed Reactions (1 result)
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N-oleoyl-phytoceramide + H2O = phytosphingosine + oleate
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Product in Enzyme-catalyzed Reactions (1 result)
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oleoyl-CoA + dihydrosphingosine = N-(oleoyl)-dihydrosphingosine + CoA
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Enzyme Kinetic Parameters
References & Links
Literature References (1)
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Alkaline ceramidase 3 (ACER3) hydrolyzes unsaturated long-chain ceramides, and its down-regulation inhibits both cell proliferation and apoptosis
2010
Hu, W.; Xu, R.; Sun, W.; Szulc, Z.M.; Bielawski, J.; Obeid, L.M.; Mao, C.
J. Biol. Chem.
285
7964-7976
Links to other databases for N-oleoyl-phytoceramide