Ligand Gly-Gly-Phe-Met
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Basic Ligand Information
Molecular Structure

C18H26N4O5S
Gly-Gly-Phe-Met
KWHAJHJQOWBJEG-KBPBESRZSA-N
(2-5)Met5-enkephalin, de-[Tyr]-Met-enkephalin
Roles as Enzyme Ligand
Substrate in Enzyme-catalyzed Reactions (2 results)
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Gly-Gly-Phe-Met + H2O = Gly-Gly + Phe-Met
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ATP + H2O + GGFM/out = ADP + phosphate + GGFM/in
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Product in Enzyme-catalyzed Reactions (3 results)
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Met5-enkephalin + H2O = tyrosin + (2-5)Met5-enkephalin
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[Arg0]-Met-enkephalin + H2O = Met-enkephalin + de-[Tyr]-Met-enkephalin
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ATP + H2O + GGFM/out = ADP + phosphate + GGFM/in
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Inhibitor in Enzyme-catalyzed Reactions (1 result)
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Enzyme Kinetic Parameters
kcat Value (Turnover Number) (1 result)
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Ki Value (1 result)
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References & Links
Literature References (3)
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Purification and characterization of aminopeptidase M from muscle and mucosa of the pig intestine
1995
Terashima, H.; Bunnett, N.W.
J. Gastroenterol.
30
696-704
Cell-specific activity of neprilysin 2 isoforms and enzymic specificity compared with neprilysin
2002
Rose, C.; Voisin, S.; Gros, C.; Schwartz, J.C.; Ouimet, T.
Biochem. J.
363
697-705
Arabidopsis OPT6 is an oligopeptide transporter with exceptionally broad substrate specificity
2009
Pike, S.; Patel, A.; Stacey, G.; Gassmann, W.
Plant Cell Physiol.
50
1923-1932
Links to other databases for Gly-Gly-Phe-Met