Ligand 5-methoxy-2,5-dioxopentanoic acid

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Basic Ligand Information

Molecular Structure
Picture of 5-methoxy-2,5-dioxopentanoic acid (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C6H8O5
5-methoxy-2,5-dioxopentanoic acid
SEMQYOVMBDIELH-UHFFFAOYSA-N
Synonyms:
2-oxo-pentandioate-5-methyl ester, 2-oxoglutamate-5-methylester, 2-oxoglutarate-5-methylester, 2-Oxoglutarate-5-methyl ester, 2-oxoglutarate 4-methyl ester, delta-methyl 2-oxoglutarate, gamma-monomethyl-2-oxoglutarate

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
5-methoxy-2,5-dioxopentanoic acid + H2O = methanol + 2-oxoglutaric acid
show the reaction diagram
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delta-methyl 2-oxoglutarate + H2O = ?
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
glyoxylate + glutamic acid 4-methyl ester = glycine + 2-oxoglutarate 4-methyl ester
show the reaction diagram
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gamma-monomethyl-2-oxoglutaramate + H2O = gamma-monomethyl-2-oxoglutarate + NH3
show the reaction diagram
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
134.5
-
pH 7.2, 30°C

KM Value (1 result)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.012
-
pH 7.2, 30°C

References & Links

Links to other databases for 5-methoxy-2,5-dioxopentanoic acid

ChEBI
PubChem
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PubChem