Ligand ribostamycin

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

Basic Ligand Information

Molecular Structure
Picture of ribostamycin (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C17H34N4O10
ribostamycin
NSKGQURZWSPSBC-SSXIAAKRSA-N

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (15 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
acetyl-CoA + ribostamycin = CoA + N2'-acetylribostamycin
show the reaction diagram
-
4-(gamma-L-glutamylamino)-(S)-2-hydroxylbutanoyl-[BtrI acyl-carrier protein] + ribostamycin = gamma-L-glutamyl-butirosin B + BtrI acyl-carrier protein
show the reaction diagram
-
UDP-N-acetyl-alpha-D-glucosamine + ribostamycin = UDP + 2'''-acetyl-6'''-hydroxyneomycin C
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
5''-phosphoribostamycin + H2O = ribostamycin + phosphate
show the reaction diagram
-
-

Inhibitor in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
pH-dependent inhibition
-

3D Structure of Enzyme-Ligand-Complex (PDB) (4 results)

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (17 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (15 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

Ki Value (2 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.07
-
-
0.0059
-
pH 7.6, 25C

References & Links

Links to other databases for ribostamycin

ChEBI
PubChem
-
PubChem