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Ligand Adenylyl-[L-glutamate:ammonia ligase (ADP-forming)] Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Basic Ligand Information Molecular Structure
C2 0 H2 2 N7 O9 PR2
Adenylyl-[L-glutamate:ammonia ligase (ADP-forming)]
[L-glutamate:ammonia ligase (ADP-forming)]-O4-(5'-adenylyl)-L-tyrosine
Roles as Enzyme Ligand
In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)
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adenylyl-[L-glutamate:ammonia ligase (ADP-forming)] + H2O = ?
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Substrate in Enzyme-catalyzed Reactions (5 results)
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[L-glutamate:ammonia ligase (ADP-forming)]-O4-(5'-adenylyl)-L-tyrosine + H2O = adenylate + [L-glutamate:ammonia ligase (ADP-forming)]-L-tyrosine
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adenylyl-[L-glutamate:ammonia ligase (ADP-forming)] + H2O = ?
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adenylyl-[L-glutamate:ammonia ligase (ADP-forming)] + H2O = adenylate + [L-glutamate:ammonia ligase (ADP-forming)]
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[L-glutamate:ammonia ligase (ADP-forming)]-O4-(5'-adenylyl)-L-tyrosine + H2O = adenylate + [L-glutamate:ammonia ligase (ADP-forming)]-L-tyrosine
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[L-glutamate:ammonia ligase (ADP-forming)]-O4-(5'-adenylyl)-L-tyrosine + phosphate = [L-glutamate:ammonia ligase (ADP-forming)]-L-tyrosine + ADP
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Enzyme Kinetic Parameters
KM Value (2 results)
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0.004
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calculated as adenylyl groups removed from substrate
References & Links Literature References (4)
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Characterization of a glutamine synthetase b activating (deadenylylating) enzyme system in Escherichia coli
1969
Heilmeyer, L.; Battig, F.; Holzer, H.
Eur. J. Biochem.
9
259-262
The glutamine synthetase deadenylylating enzyme system from Escherichia coli. Resolution into two components, specific nucleotide stimulation, and cofactor requirements
1969
Shapiro, B.M.
Biochemistry
8
659-670
Escherichia coli glutamine synthetase adenylyltransferase (ATase, EC 2.7.7.49): kinetic characterization of regulation by PII, PII-UMP, glutamine, and alpha-ketoglutarate
2007
Jiang, P.; Mayo, A.E.; Ninfa, A.J.
Biochemistry
46
4133-4146
The regulation of Escherichia coli glutamine synthetase revisited: Role of 2-ketoglutarate in the regulation of glutamine synthetase adenylylation state
1998
Jiang, P.; Peliska, J.; Ninfa, A.
Biochemistry
37
12802-12810
Links to other databases for Adenylyl-[L-glutamate:ammonia ligase (ADP-forming)]