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BRENDA support

Ligand rhodopsin

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Basic Ligand Information

Molecular Structure
Picture of rhodopsin (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
HOR
rhodopsin
Synonyms:
R1OH, R2-OH, R2OH, ROH, [receptor-protein]

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
ATP + rhodopsin = ADP + phosphorylated rhodopsin
show the reaction diagram
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ATP + rhodopsin = ADP + phosphorylated rhodopsin
show the reaction diagram
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ATP + [receptor-protein] = ADP + [receptor-protein] phosphate
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (11 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2 thioredoxin + ROOH = thioredoxin disulfide + H2O + ROH
show the reaction diagram
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NADH + ROOH + H+ = NAD+ + 2 ROH
show the reaction diagram
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a [lipoyl-carrier protein]-N6-[(R)-dihydrolipoyl]-L-lysine + ROOH = a [lipoyl-carrier protein]-N6-lipoyl-L-lysine + H2O + ROH
show the reaction diagram
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glutathione + ROOH = glutathione disulfide + ROH + H2O
show the reaction diagram
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RH + [reduced NADPH-hemoprotein reductase] + O2 = ROH + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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phosphorylated rhodopsin + H2O = rhodopsin + phosphate
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (11 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
ATP + [receptor-protein] = ADP + [receptor-protein] phosphate
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (12 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2 thioredoxin + ROOH = thioredoxin disulfide + H2O + ROH
show the reaction diagram
-
NADH + ROOH + H+ = NAD+ + 2 ROH
show the reaction diagram
-
a [lipoyl-carrier protein]-N6-[(R)-dihydrolipoyl]-L-lysine + ROOH = a [lipoyl-carrier protein]-N6-lipoyl-L-lysine + H2O + ROH
show the reaction diagram
-
RH + [reduced NADPH-hemoprotein reductase] + O2 = ROH + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
-
phosphorylated rhodopsin + H2O = rhodopsin + phosphate
show the reaction diagram
-

Activator in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
interaction of enzyme with light-activated rhodopsin or truncated rhodopsin lacking its C-terminal phosphorylation sites activates peptide phosphorylation, at lower concentrations, enhances both the affinity and catalytic efficiency for peptide phosphorylation, but intact light-activated rhodopsin slightly inhibits the phosphorylation of RRREEEEESAAA
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Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
intact light-activated rhodopsin slightly inhibits phosphorylation of RRREEEEESAAA
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (2 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (25 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

References & Links

Links to other databases for rhodopsin

ChEBI
PubChem
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