Ligand (6R)-N10-formyltetrahydrofolate

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Basic Ligand Information

Molecular Structure
Picture of (6R)-N10-formyltetrahydrofolate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C20H23N7O7
(6R)-N10-formyltetrahydrofolate
AUFGTPPARQZWDO-YPMHNXCESA-N
Synonyms:
(6 R)-N10-formyl-tetrahydrofolate, (6 R)-N10-formyltetrahydrofolate, (6R)-10-formyl-5,6,7,8-tetrahydropteroylglutamate, L-(+)-10-formyltetrahydrofolate

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (2 results)

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EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(6R)-N10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide = (6R)-tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide
show the reaction diagram
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ATP + (6R)-10-formyl-5,6,7,8-tetrahydropteroylglutamate + L-glutamate = ADP + phosphate + (6R)-10-formyl-5,6,7,8-tetrahydropteroyl-Glu2
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (1 result)

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EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
excellent competitive inhibitor
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (4 results)

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EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (4 results)

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EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

References & Links

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Links to other databases for (6R)-N10-formyltetrahydrofolate

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ChEBI
PubChem
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PubChem