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Ligand N2-succinyl-L-arginine Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Basic Ligand Information Molecular Structure
C1 0 H1 8 N4 O5
N2-succinyl-L-arginine
UMOXFSXIFQOWTD-LURJTMIESA-N
2-N-succinyl-L-arginine, N-Succinyl-L-Arg, N2-succinylarginine
Show all BRENDA pathways known for N2-succinyl-L-arginine
Roles as Enzyme Ligand
In Vivo Product in Enzyme-catalyzed Reactions (1 result)
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succinyl-CoA + L-arginine = CoA + N2-succinyl-L-arginine
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Substrate in Enzyme-catalyzed Reactions (2 results)
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N2-succinyl-L-arginine + H2O = N2-succinyl-L-ornithine + NH3 + CO2
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N-succinyl-L-Arg = N-succinyl-D-Arg
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Product in Enzyme-catalyzed Reactions (1 result)
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succinyl-CoA + L-arginine = CoA + N2-succinyl-L-arginine
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Enzyme Kinetic Parameters
kcat Value (Turnover Number) (1 result)
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KM Value (2 results)
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-999
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low specific rotation prevented kinetic analysis
References & Links Literature References (3)
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Occurrence of succinyl derivatives in the catabolism of arginine in Pseudomonas cepacia
1985
Vander Wauven, C.; Stalon, V.
J. Bacteriol.
164
882-886
Crystal structure of N-succinylarginine dihydrolase AstB, bound to substrate and product, an enzyme from the arginine catabolic pathway of Escherichia coli
2005
Tocilj, A.; Schrag, J.D.; Li, Y.; Schneider, B.L.; Reitzer, L.; Matte, A.; Cygler, M.
J. Biol. Chem.
280
15800-15808
Evolution of enzymatic activities in the enolase superfamily: N-succinylamino acid racemase and a new pathway for the irreversible conversion of D- to L-amino acids
2006
Sakai, A.; Xiang, D.F.; Xu, C.; Song, L.; Yew, W.S.; Raushel, F.M.; Gerlt, J.A.
Biochemistry
45
4455-4462
Links to other databases for N2-succinyl-L-arginine