print visible entries

print all entries

Ligand N-acetyl-beta-D-glucosaminyl-1,3-N-acetyl-D-galactosaminyl-alpha-benzyl

Basic Ligand Information

Molecular Structure

close all tables

open all tables

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (1 result)

top print hide

Show Substrate (1 entry)

EC NUMBER

LITERATURE

REACTION DIAGRAM

REACTION

ENZYME 3D STRUCTURE

2.4.1.148

488370, 638139, 638138, 638282

UDP-N-acetyl-D-glucosamine + N-acetyl-beta-D-glucosaminyl-1,3-N-acetyl-alpha-D-galactosaminyl-benzyl = UDP + N-acetyl-beta-D-glucosaminyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,3)-N-acetyl-alpha-D-galactosaminyl-benzyl

-

Product in Enzyme-catalyzed Reactions (1 result)

top print hide

Show Product (1 entry)

EC NUMBER

LITERATURE

REACTION DIAGRAM

REACTION

ENZYME 3D STRUCTURE

2.4.1.147

488370, 638139, 638138, 638140,

UDP-N-acetyl-D-glucosamine + N-acetyl-alpha-D-galactosaminyl-benzyl = UDP + N-acetyl-beta-D-glucosaminyl-1,3-N-acetyl-alpha-D-galactosaminyl-benzyl

-

Enzyme Kinetic Parameters

K_M Value (2 results)

top print hide

Show KM Value (2 entries)

COMMENTARY

EC NUMBER

KM VALUE [MM]

KM VALUE MAXIMUM [MM]

LITERATURE

colon

2.4.1.148

0.6

-

488370, 638139

stomach

2.4.1.148

1.8

-

488370

References & Links

Literature References (5)

top print hide

Show Reference (5 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

488370

2560125

High-performance liquid chromatography assays for N-acetylglucosaminyltransferases involved in N- and O-glycan synthesis

1989

Schachter, H.; Brockhausen, I.; Hull, E.

Methods Enzymol.

179

351-397

638138

6226356

The separation by liquid chromatography (under elevated pressure) of phenyl, benzyl, and O-nitrophenyl glycosides of oligosaccharides. Analysis of substrates and products for four N-acetyl-D-glucosaminyl-transferases involved in mucin synthesis

1983

Brockhausen, I.; Rachaman, E.S.; Matta, K.L.; Schachter, H.

Carbohydr. Res.

120

3-16

638139

3160388

Mucin synthesis. UDP-GlcNAc:GalNAc-R beta 3-N-acetylglucosaminyltransferase and UDP-GlcNAc:GlcNAc beta 1-3GalNAc-R (GlcNAc to GalNAc) beta 6-N-acetylglucosaminyltransferase from pig and rat colon mucosa

1985

Brockhausen, I.; Matta, K.L.; Orr, J.; Schachter, H.

Biochemistry

24

1866-1874

638140

7655172

Synthesis of O-glycan core 3: characterization of UDP-GlcNAc:GalNAc-R beta3-N-acetyl-glucosaminyltransferase activity from colonic mucosal tissues and lack of the activity in human cancer cell lines

1995

Vavasseur, F.; Yang, J.M.; Dole, K.; Paulsen, H.; Brockhausen, I.

Glycobiology

5

351-357

638282

9299421

Pilot scale expression and purification of soluble protein A tagged beta1,6N-acetylglucosaminyltransferase in CHO cells

1997

Zeng, S.; Dinter, A.; Eisenkratzer, D.; Biselli, M.; Wandrey, C.; Berger, E.G.

Biochem. Biophys. Res. Commun.

237

653-658

Links to other databases for N-acetyl-beta-D-glucosaminyl-1,3-N-acetyl-D-galactosaminyl-alpha-benzyl

top print hide

Show Links (1 entry)

ChEBI

PubChem

-