Ligand 5'-chloro-5'-deoxyadenosine

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Basic Ligand Information

Molecular Structure
Picture of 5'-chloro-5'-deoxyadenosine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C10H12ClN5O3
5'-chloro-5'-deoxyadenosine
IYSNPOMTKFZDHZ-KQYNXXCUSA-N
Synonyms:
5'-chloro-5'-deoxy-adenosine, 5'-deoxy-5'-chloroadenosine, 5-deoxy-5'-chloroadenosine, 5-deoxy-5-chloroadenosine
Pathway Source
Pathways

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
5-deoxy-5-chloroadenosine + L-methionine = S-adenosyl-L-methionine + chloride
show the reaction diagram

In Vivo Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Substrate in Enzyme-catalyzed Reactions (17 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
5'-chloro-5'-deoxy-adenosine + phosphate = 5-chloro-5-deoxy-D-ribose 1-phosphate + adenine
show the reaction diagram
-
5'-deoxy-5'-chloroadenosine + H2O = adenosine + ?
show the reaction diagram
-
5'-chloro-5'-deoxyadenosine + H2O = ?
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
S-adenosyl-L-methionine + chloride = 5'-deoxy-5'-chloroadenosine + L-methionine
show the reaction diagram
-

3D Structure of Enzyme-Ligand-Complex (PDB) (2 results)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (9 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.0052
-
at pH 8.5 and 37°C

KM Value (9 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.41
-
at pH 8.5 and 37°C

References & Links

Links to other databases for 5'-chloro-5'-deoxyadenosine

ChEBI
PubChem
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PubChem