Ligand Na+

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Basic Ligand Information

Molecular Structure
Picture of Na+ (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
Na
Na+
FCXZBWSIAGGPCB-YFKPBYRVSA-N
Synonyms:
Na+/[side 1], Na+/[side 2], Na+in, Na+ in, Na+out, Na+ out, Na+out (n = 1-2), Na+[side 1], Na+[side 2], Na/+in, Na/+out, sodium
Pathway Source
Pathways

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (70 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
ATP + H2O + Na+[side 1] = ADP + phosphate + Na+[side 2]
show the reaction diagram
-
oxaloacetate + Na+[side 1] = pyruvate + CO2 + Na+[side 2]
show the reaction diagram
-
(S)-methylmalonyl-CoA + Na+[side 1] + H+[side 2] = propanoyl-CoA + CO2 + Na+[side 2]
show the reaction diagram
-

In Vivo Product in Enzyme-catalyzed Reactions (67 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
ATP + H2O + Na+[side 1] = ADP + phosphate + Na+[side 2]
show the reaction diagram
-
-
oxaloacetate + Na+[side 1] = pyruvate + CO2 + Na+[side 2]
show the reaction diagram
-
-
(S)-methylmalonyl-CoA + Na+[side 1] + H+[side 2] = propanoyl-CoA + CO2 + Na+[side 2]
show the reaction diagram
-
-

Substrate in Enzyme-catalyzed Reactions (143 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
ATP + H2O + Na+/in = ADP + phosphate + Na+/out
show the reaction diagram
-
ATP + H2O + Na+[side 1] = ADP + phosphate + Na+[side 2]
show the reaction diagram
-
oxaloacetate + Na+[side 1] = pyruvate + CO2 + Na+[side 2]
show the reaction diagram
-
(S)-methylmalonyl-CoA + Na+[side 1] + H+[side 2] = propanoyl-CoA + CO2 + Na+[side 2]
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (144 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
ATP + H2O + Na+/in = ADP + phosphate + Na+/out
show the reaction diagram
-
-
ATP + H2O + Na+[side 1] = ADP + phosphate + Na+[side 2]
show the reaction diagram
-
-
oxaloacetate + Na+[side 1] = pyruvate + CO2 + Na+[side 2]
show the reaction diagram
-
-
(S)-methylmalonyl-CoA + Na+[side 1] + H+[side 2] = propanoyl-CoA + CO2 + Na+[side 2]
show the reaction diagram
-

Activator in Enzyme-catalyzed Reactions (1159 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
Na+ at 25 mM stimulates expression of PrxII F
-
125 mM NaCl, 1.5 fold increase in activity
-
at 67 mM 1.5 fold activity
-
activity is enhanced by 180% with Na+ (500 mM)
-
1 mM, activation to 180% of control
-
up to 300 mM, slight activitation. Inhibitory above 500 mM
-