Ligand Thiorphan

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Basic Ligand Information

Molecular Structure
Picture of Thiorphan (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C12H15NO3S
Thiorphan
LJJKNPQAGWVLDQ-UHFFFAOYSA-N
Synonyms:
DL-thiorphan, DL-[N-(3-mercapto-2-benzylpropanoyl)]glycine, N-(2-benzyl-3-sulfanylpropanoyl)glycine

Show all pahtways known for Show all pathways known for Thiorphan

Roles as Enzyme Ligand

Inhibitor in Enzyme-catalyzed Reactions (28 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
less effective inhibitor; less effective inhibitor
-
slight inhibition at 0.1 mM
-
weak, IC50: 0.0001 mM
-
0.001 mM and 0.0001 mM, 35% and 47% inhibition, respectively
-

Enzyme Kinetic Parameters

Ki Value (14 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.0015
-
pH 7.4, 37°C

IC50 Value (6 results)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
0.0001
-
weak, IC50: 0.0001 mM

References & Links

Links to other databases for Thiorphan

ChEBI
PubChem
ChEBI
PubChem