Ligand peptide

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Basic Ligand Information

Molecular Structure
Picture of peptide (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C6H8N4O3R4
peptide
AOIHJKREJFPKDL-SCSAIBSYSA-N
Synonyms:
a peptide, peptides

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (18 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
acetyl-CoA + peptide = CoA + Nalpha-acetylpeptide
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acetyl-CoA + peptide = CoA + Nalpha-acetylpeptide
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acetyl-CoA + peptide = CoA + Nalpha-acetylpeptide
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Peptides + H2O = ?
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Peptides + H2O = ?
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Peptides + H2O = ?
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peptide + H2O = ?
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Peptides + H2O = ?
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peptide + H2O = peptide proteolytically cleaved into fragments or single amino acids
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peptide + H2O = hydrolyzed peptide
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peptide + H2O = hydrolyzed peptide
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peptide + H2O = hydrolyzed peptide
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peptide + H2O = hydrolyzed peptide
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Peptides + H2O = ?
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In Vivo Product in Enzyme-catalyzed Reactions (70 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
Met-peptide + H2O = Met + peptide
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Xaa-peptide + H2O = Xaa + peptide
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protein + H2O = peptides
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pyroglutamyl-peptide + H2O = pyroglutamate + peptide
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proacrosin + H2O = acrosin + peptide
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pre-D1 protein + H2O = D1 protein + peptide
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polypeptide + H2O = peptides
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polypeptide + H2O = peptides
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polypeptide + H2O = peptides
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polypeptide + H2O = peptides
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intermediate of cytochrome c peroxidase + H2O = mature cytochrome c peroxidase + peptide
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polypeptide + H2O = peptides
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polypeptide + H2O = peptides
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polypeptide + H2O = peptides
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polypeptide + H2O = peptides
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polypeptide + H2O = peptides
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polypeptide + H2O = peptides
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polypeptide + H2O = peptides
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polypeptide + H2O = peptides
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polypeptide + H2O = peptides
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tyrosine aminotransferase + H2O = truncated tyrosine aminotransferase + peptide
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protein + H2O = peptides
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protein + H2O = peptides
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protein + H2O = peptides
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protein + H2O = peptides
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protein + H2O = peptides
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protein + H2O = peptides
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protein + H2O = peptides
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Smt3-precursor + H2O = SMT3 + peptide
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proproteinase A + H2O = pseudo-proteinaseA + peptide
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polypeptide + H2O = peptides
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proteins + H2O = peptides
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protein + H2O = peptides
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protein + H2O = peptides
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protein + H2O = peptides
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protein + H2O = peptides
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protein + H2O = peptides
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pro-sigmaK + H2O = sigmaK + peptide
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protein + H2O = peptides
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protein + H2O = peptides
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protein + H2O = peptides
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proteins + H2O = peptides
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proteins + H2O = peptides
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proteins + H2O = peptides
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proteins + H2O = peptides
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Nalpha-acetylated peptide + H2O = acetate + peptide
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Substrate in Enzyme-catalyzed Reactions (36 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
acetyl-CoA + peptide = CoA + Nalpha-acetylpeptide
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acetyl-CoA + peptide = CoA + Nalpha-acetylpeptide
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acetyl-CoA + peptide = CoA + Nalpha-acetylpeptide
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ATP + peptide = ADP + phospho-L-tyrosinyl-peptide
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ATP + a peptide = ADP + a phosphorylated peptide
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ATP + peptide = ADP + phosphopeptide
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ATP + peptide = ADP + phosphopeptide
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Peptides + H2O = ?
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Peptides + H2O = ?
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Peptides + H2O = ?
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peptide + H2O = ?
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Peptides + H2O = ?
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Peptide + H2O = Hydrolyzed peptide + H2O
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peptide + H2O = ?
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peptide + H2O = hydrolyzed peptide
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peptide + H2O = hydrolyzed peptide
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peptide + H2O = hydrolyzed peptide
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peptide + H2O = hydrolyzed peptide
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peptide + H2O = hydrolyzed peptide
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peptide + H2O = hydrolyzed peptide
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peptide + H2O = hydrolyzed peptide
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peptide + H2O = hydrolyzed peptide
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peptide + H2O = hydrolyzed peptide
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peptide + H2O = hydrolyzed peptide
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peptide + H2O = hydrolyzed peptide
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Peptides + H2O = ?
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Peptides + H2O = ?
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Peptides + H2O = Hydrolyzed peptides
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peptide + H2O = ?
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Product in Enzyme-catalyzed Reactions (110 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
palmitoyl-peptide + H2O = palmitate + peptide
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palmitoyl-peptide + H2O = palmitate + peptide
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phosphorylated peptide + H2O = peptide + phosphate
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L-amino acid-peptide + H2O = amino acid + peptide
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Xaa-peptide + H2O = Xaa + peptide
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L-prolyl-peptide + H2O = L-proline + peptide
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L-prolyl-peptide + H2O = L-proline + peptide
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protein + H2O = peptides
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ubiquitinyl-peptide + H2O = ubiquitin + peptide
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pyroglutamyl-peptide + H2O = pyroglutamate + peptide
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proacrosin + H2O = acrosin + peptide
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pre-D1 protein + H2O = D1 protein + peptide
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polypeptide + H2O = peptides
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polypeptide + H2O = peptides
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human parathyroid hormone(13-34) + H2O = peptides
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peptidyl-p-nitroanilide + H2O = p-nitroaniline + peptide
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factor IX + H2O = factor IXa + peptide
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porcine brain tubulin + H2O = peptides
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peptidyl-7-amido-4-methyl-coumarin + H2O = 7-amino-4-methyl-coumarin + peptide
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polypeptide + H2O = peptides
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peptide-4-nitroanilide + H2O = peptide + 4-nitroaniline
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intermediate of cytochrome c peroxidase + H2O = mature cytochrome c peroxidase + peptide
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Arc-ssrA + H2O = peptides
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polypeptide + H2O = peptides
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polypeptide + H2O = peptides
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polypeptide + H2O = peptides
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polypeptide + H2O = peptides
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polypeptide + H2O = peptides
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polypeptide + H2O = peptides
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polypeptide + H2O = peptides
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polypeptide + H2O = peptides
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polypeptide + H2O = peptides
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trypsinogen + H2O = trypsin + peptide
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azocasein + H2O = azopeptide + peptides
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tyrosine aminotransferase + H2O = truncated tyrosine aminotransferase + peptide
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protein + H2O = peptides
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protein + H2O = peptides
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protein + H2O = peptides
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protein + H2O = peptides
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protein + H2O = peptides
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protein + H2O = peptides
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Smt3-precursor + H2O = SMT3 + peptide
show the reaction diagram
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proproteinase A + H2O = pseudo-proteinaseA + peptide
show the reaction diagram
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polypeptide + H2O = peptides
show the reaction diagram
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proteins + H2O = peptides
show the reaction diagram
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protein + H2O = peptides
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protein + H2O = peptides
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protein + H2O = peptides
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protein + H2O = peptides
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pro-sigmaK + H2O = sigmaK + peptide
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protein + H2O = peptides
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protein + H2O = peptides
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protein + H2O = peptides
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proteins + H2O = peptides
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proteins + H2O = peptides
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Nalpha-acetylated peptide + H2O = acetate + peptide
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Inhibitor in Enzyme-catalyzed Reactions (15 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
especially those with COOH-terminal glycine residues
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peptides homologous to the Gly734 site of pyruvate formate-lyase that are active as substrates
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diacylhydroxylamine derivatives of Xaa-Pro or Xaa-Ala peptides. Different oligopeptides with N-terminal Xaa-Pro-sequences
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containing either of the cleavage site sequence found in ubiquitin polymers, but not unrelated peptides
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acyloxymethyl ketone derivative of human SCC1 cleavage site peptide, chloromethyl ketone derivatives of the yeast Scc1 cleavage site
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29 amino acid peptide liberated in activation of pepsinogen
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containing the hydroxamic acid, N-hydroxypeptide and thiol functional groups
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TFLPQPRCSALLRYLSEDGVIVPS and YDFYWW, no inhibition of the enzyme from Bacillus pasteurii and Canavalia ensiformis
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study of the inhibition of enzyme catalyzed reduction of insulin by GSH by peptides of various length and amino acid composition
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
67
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KM Value (4 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

References & Links

Links to other databases for peptide

ChEBI
PubChem
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PubChem