Ligand N-acetylmuramic acid

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Basic Ligand Information

Molecular Structure
Picture of N-acetylmuramic acid (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C11H19NO8
N-acetylmuramic acid
MNLRQHMNZILYPY-MKFCKLDKSA-N
Synonyms:
2-acetamido-3-O-(D-1-carboxyethyl)-2-deoxy-D-glucose, MurNAc, N-acetyl-D-muramate, N-acetyl-D-muramate[side 1], N-acetylmuramate, N-acetyl muramic acid

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
ATP + N-acetyl-D-muramate = ADP + N-acetyl-alpha-D-muramate 1-phosphate
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
N-acetyl-D-muramate 6-phosphate + H2O = N-acetyl-D-muramate + phosphate
show the reaction diagram
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N-acetylmuramoyl-L-alanine + H2O = N-acetylmuramate + L-alanine
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
N-acetylmuramic acid + O2 = ?
show the reaction diagram
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ATP + N-acetyl-D-muramate = ADP + N-acetyl-alpha-D-muramate 1-phosphate
show the reaction diagram
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CTP + N-acetylmuramic acid = diphosphate + CMP-N-acetylmuramic acid
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
N-acetyl-D-muramate 6-phosphate + H2O = N-acetyl-D-muramate + phosphate
show the reaction diagram
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O-2-acetamido-2-deoxy-beta-D-glucopyranosyl-(1-4)-2-acetamido-3-O-(D-1-carboxyethyl)-2-deoxy-D-glucose + H2O = 2-acetamido-2-deoxy-beta-D-glucopyranose + 2-acetamido-3-O-(D-1-carboxyethyl)-2-deoxy-D-glucose
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
MurAc, 1 mM, activity 76,9%
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
5.15
-
pH not specified in the publication, temperature not specified in the publication

KM Value (2 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
33
-
-
0.08
-
pH not specified in the publication, temperature not specified in the publication

References & Links

Links to other databases for N-acetylmuramic acid

ChEBI
PubChem
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PubChem