Ligand 2,3-Dihydroxybiphenyl

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Basic Ligand Information

Molecular Structure
Picture of 2,3-Dihydroxybiphenyl (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C12H10O2
2,3-Dihydroxybiphenyl
YKOQAAJBYBTSBS-UHFFFAOYSA-N
Synonyms:
3-Phenyl-1,2-dihydroxybenzene, 3-phenylcatechol, biphenyl-2,3-diol, cis-2,3-dihydroxybiphenyl

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (12 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

In Vivo Product in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-hydroxybiphenyl + NADH + O2 = 2,3-dihydroxybiphenyl + NAD+ + H2O
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (30 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2,3-dihydroxybiphenyl + O2 = ?
show the reaction diagram
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biphenyl-2,3-diol + NADH + H+ + O2 = (4R,5S)-4,5-dihydroxy-3-phenylcyclohex-2-en-1-one + NAD+
show the reaction diagram
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2,3-dihydroxybiphenyl + NADH + H+ + O2 = ?
show the reaction diagram
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biphenyl-2,3-diol + H2O = ?
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (13 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
3-hydroxybiphenyl + FMNH2 + O2 = 2,3-dihydroxybiphenyl + FMN + H2O
show the reaction diagram
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-

Inhibitor in Enzyme-catalyzed Reactions (21 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
inhibits reaction with 2-hydroxybiphenyl
-
the growth of strain BCG is retarded when the cultures are incubated either in the presence of 2,3-dihydroxybiphenyl on both solid and liquid media
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competitive
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3D Structure of Enzyme-Ligand-Complex (PDB) (31 results)

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (15 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
200
-
pH and temperature not specified in the publication

KM Value (26 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.0012
-
pH and temperature not specified in the publication

Ki Value (3 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
3
-
reversible substrate inhibition
0.9
-
-
0.4
-
pH 7.0, 28°C, recombinant enzyme

References & Links

Links to other databases for 2,3-Dihydroxybiphenyl

ChEBI
PubChem
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PubChem