Ligand 13-(S)-hydroxyoctadecadienoic acid
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Basic Ligand Information
Molecular Structure

C18H32O3
13-(S)-hydroxyoctadecadienoic acid
RXTABFLLDULHQN-MOQGOERRSA-N
13(S)-hydroxyoctadecadienoic acid, 13-S-hydroxyoctadecadienoic acid
Roles as Enzyme Ligand
Product in Enzyme-catalyzed Reactions (3 results)
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linoleic acid + O2 = 13(S)-hydroxyoctadecadienoic acid
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linoleic acid + O2 = 13(S)-hydroxyoctadecadienoic acid
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linoleic acid + O2 = 13-S-hydroxyoctadecadienoic acid
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Activator in Enzyme-catalyzed Reactions (1 result)
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allosteric effector, which changes the conformation of 15-hLO-2 such that substrate affinity toward linoleic acid is significantly increased
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Enzyme Kinetic Parameters
References & Links
Literature References (1)
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Kinetic and structural investigations of the allosteric site in human epithelial 15-lipoxygenase-2
2009
Wecksler, A.T.; Kenyon, V.; Garcia, N.K.; Deschamps, J.D.; van der Donk, W.A.; Holman, T.R.
Biochemistry
48
8721-8730
Links to other databases for 13-(S)-hydroxyoctadecadienoic acid