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BRENDA support

Ligand gamma-Glu-Leu

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Basic Ligand Information

Molecular Structure
Picture of gamma-Glu-Leu (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
Molfile
C11H20N2O5
gamma-Glu-Leu
MYFMARDICOWMQP-YUMQZZPRSA-N
Synonyms:
5-L-glutamyl-L-Leu, 5-L-glutamyl-L-leucine, 5-L-glutamyl-Leu, gamma-glutamyl-L-leucine, gamma-glutamyl L-leucine, gamma-glutamylleucine, gamma-L-Glu-L-Leu, gamma-L-Glu-L-leucine, gamma-L-glutamyl-L-leucine, L-gamma-glutamyl-L-leucine

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
gamma-glutamyl L-leucine + H2O = L-leucine + L-glutamate
show the reaction diagram
-
5-L-glutamyl-L-leucine = 5-oxoproline + L-leucine
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
5-L-glutamyl-5-L-glutamyl-L-leucine = 5-oxoproline + 5-L-glutamyl-L-leucine
show the reaction diagram
-

Inhibitor in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
5 mM, 10% inhibition
-
about 60% inhibition at 10 mM
-

Enzyme Kinetic Parameters

KM Value (2 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.0334
-
isoform GGT1, in 100 mM Na2HPO4, 3.2 mM KCl, 1.8 mM KH2PO4, and 27.5 mM NaCl, pH 7.4, at 37°C
0.0334
-
pH 7.4, 37°C

References & Links

Links to other databases for gamma-Glu-Leu

EXTERNAL LINKS