Ligand 4-Fumarylacetoacetate

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Basic Ligand Information

Molecular Structure
Picture of 4-Fumarylacetoacetate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C8H8O6
4-Fumarylacetoacetate
GACSIVHAIFQKTC-OWOJBTEDSA-N
Synonyms:
Fumarylacetoacetate


Show all pahtways known for Show all BRENDA pathways known for 4-Fumarylacetoacetate

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
4-fumarylacetoacetate + H2O = acetoacetate + fumarate
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
4-maleylacetoacetate = 4-fumarylacetoacetate
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
4-fumarylacetoacetate + H2O = acetoacetate + fumarate
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
homogentisate + O2 = 4-fumarylacetoacetate
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
reduces MAT I/III activity
-

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.1
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pH 7.4, 22°C

KM Value (4 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

References & Links

Links to other databases for 4-Fumarylacetoacetate

ChEBI
PubChem
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PubChem