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Ligand 1-acylglycerophosphoinositol

Basic Ligand Information

Molecular Structure

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Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (2 results)

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Show Substrate (2 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.3.1.23

arachidonoyl-CoA + 1-acyl-sn-glycero-3-phosphoinositol = CoA + 1-acyl-2-arachidonoyl-sn-glycero-3-phosphoinositol

486637, 486648, 486626

-

2.3.1.23

oleoyl-CoA + 1-acyl-sn-glycero-3-phosphoinositol = CoA + 1-acyl-2-oleoyl-sn-glycero-3-phosphoinositol

486620, 486650

-

2.3.1.23

2 entries

Product in Enzyme-catalyzed Reactions (4 results)

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Show Product (4 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

3.1.1.52

1-acyl-2-arachidonoyl-sn-glycerol-3-phosphoinositol + H2O = 1-acylglycerophosphoinositol + arachidonic acid

80968, 80967

-

3.1.1.52

1-acyl-2-oleoyl-sn-glycerol-3-phosphoinositol + H2O = 1-acylglycerophosphoinositol + oleic acid

80966, 0

-

3.1.1.52

1-acyl-2-palmitoyl-sn-glycerol-3-phosphoinositol + H2O = 1-acylglycerophosphoinositol + palmitic acid

80967

-

3.1.1.52

1-acyl-2-stearoyl-sn-glycerol-3-phosphoinositol + H2O = 1-acylglycerophosphoinositol + stearic acid

80967

-

3.1.1.52

4 entries

Enzyme Kinetic Parameters

K_M Value (1 result)

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Show KM Value (1 entry)

EC NUMBER

KM VALUE [MM]

KM VALUE MAXIMUM [MM]

COMMENTARY

LITERATURE

2.3.1.23

0.0138

-

-

486620

References & Links

Literature References (8)

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Show Reference (8 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

80966

7083039

The purification and characterization of a phospholipase A2 activity from the 106000 x g pellet (microsomal fraction) of bovine brain acting on phosphatidylinositol

1981

Gray, N.C.C.; Strickland, K.P.

Can. J. Biochem.

60

108-117

80967

7087686

On the specificity of a phospholipase A2 purified from the 106,000 X g pellet of bovine brain

1982

Gray, N.C.C.; Strickland, K.P.

Lipids

17

91-96

80968

3139045

Phospholipase A2 in macrophage plasma membrane releases arachidonic acid from phosphatidylinositol

1988

Shibata, Y.; Abiko, Y.; Takiguchi, H.

Biochim. Biophys. Acta

971

121-126

486620

7408877

The kinetic properties of oleoyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase from mouse-brain microsomes

1980

Wise, R.W.; Sun, G.Y.; MacQuarrie, R.

Eur. J. Biochem.

109

201-206

486626

2729998

Purification and kinetic properties of lysophosphatidylinositol acyltransferase from bovine heart muscle microsomes and comparison with lysophosphatidylcholine acyltransferase

1989

Sanjanwala, M.; Sun, G.Y.; MacQuarrie, R.

Arch. Biochem. Biophys.

271

407-413

486637

7357017

Extraction and partial purification of acyl-CoA:1-acyl-sn-glycero-3-phosphocholine acyltransferase from rat liver microsomes

1980

Hasegawa-Sasaki, H.; Ohno, K.

Biochim. Biophys. Acta

617

205-217

486648

8611569

Formation of vesicles by the action of acyl-CoA:1-acyllsophosphatidylcholine acyltransferase from rat liver microsomes: optimal solubilization conditions and analysis of lipid composition and enzyme activity

1996

Fyrst, H.; Pham, D.V.; Lubin, B.H.; Kuypers, F.A.

Biochemistry

35

2644-2650

486650

9126285

Acyl-CoA:lysophosphatidylcholine acyltransferase activity in bovine retina rod outer segments

1997

Castagnet, P.I.; Giusto, N.M.

Arch. Biochem. Biophys.

340

124-134

Links to other databases for 1-acylglycerophosphoinositol

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Show Links (1 entry)