Ligand papaverine

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Basic Ligand Information

Molecular Structure
Picture of papaverine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C20H21NO4
papaverine
XQYZDYMELSJDRZ-UHFFFAOYSA-N
Synonyms:
1-(3,4-dimethoxybenzyl)-6,7-dimethoxyisoquinoline

Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(RS)-tetrahydropapaverine + O2 = papaverine + H2O2
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
papaverine + 2-oxoglutarate + O2 = ?
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(RS)-tetrahydropapaverine + O2 = papaverine + H2O2
show the reaction diagram
-
-

Inhibitor in Enzyme-catalyzed Reactions (19 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
about 5% inhibition at 0.1 mM
-
weak, not in the dark
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binding structure, molecular modeling, overview
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3D Structure of Enzyme-Ligand-Complex (PDB) (5 results)

Enzyme Kinetic Parameters

Ki Value (12 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

IC50 Value (9 results)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE

References & Links

Links to other databases for papaverine

ChEBI
PubChem
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PubChem