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Ligand 5alpha-cholest-22-en-3beta-ol Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Basic Ligand Information Molecular Structure
C2 7 H4 6 O
5alpha-cholest-22-en-3beta-ol
BWGQUGBECNWWDB-PNAUCWDRSA-N
Roles as Enzyme Ligand
In Vivo Substrate in Enzyme-catalyzed Reactions (3 results)
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5alpha-cholest-22-en-3beta-ol + ferrocytochrmoe b5 + H+ + O2 = cholesta-5,22-dien-3beta-ol + ferricytochrome b5 + 2 H2O
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5alpha-cholest-22-en-3beta-ol + O2 + NADH + H+ = 5alpha-cholesta-7,22-dien-3beta-ol + NAD+ + H2O
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5alpha-cholest-22-en-3beta-ol + O2 + NADPH + H+ = 5alpha-cholesta-7,22-dien-3beta-ol + NADP+ + H2O
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Substrate in Enzyme-catalyzed Reactions (3 results)
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5alpha-cholest-22-en-3beta-ol + ferrocytochrmoe b5 + H+ + O2 = cholesta-5,22-dien-3beta-ol + ferricytochrome b5 + 2 H2O
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5alpha-cholest-22-en-3beta-ol + O2 + NADH + H+ = 5alpha-cholesta-7,22-dien-3beta-ol + NAD+ + H2O
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5alpha-cholest-22-en-3beta-ol + O2 + NADPH + H+ = 5alpha-cholesta-7,22-dien-3beta-ol + NADP+ + H2O
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Enzyme Kinetic Parameters
References & Links Literature References (2)
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C-5(6) sterol desaturase from Tetrahymena thermophila: Gene identification and knockout, sequence analysis, and comparison to other C-5(6) sterol desaturases
2009
Nusblat, A.D.; Najle, S.R.; Tomazic, M.L.; Uttaro, A.D.; Nudel, C.B.
Eukaryot. Cell
8
1287-1297
The sterol-C7 desaturase from the ciliate Tetrahymena thermophila is a Rieske oxygenase, which is highly conserved in animals
2013
Najle, S.R.; Nusblat, A.D.; Nudel, C.B.; Uttaro, A.D.
Mol. Biol. Evol.
30
1630-1643
Links to other databases for 5alpha-cholest-22-en-3beta-ol