Ligand G418

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Basic Ligand Information

Molecular Structure
Picture of G418 (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C20H40N4O10
G418
BRZYSWJRSDMWLG-HXGJMTBFSA-N
Synonyms:
Antibiotic G-418
Pathway Source
Pathways
KEGG
Biosynthesis of secondary metabolites, Neomycin, kanamycin and gentamicin biosynthesis

Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

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EC NUMBER
LITERATURE
REACTION DIAGRAM
PROVEN IN VIVO REACTION
ENZYME 3D STRUCTURE
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show the reaction diagram
S-adenosyl-L-methionine + gentamicin X2 = S-adenosyl-L-homocysteine + G418
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Substrate in Enzyme-catalyzed Reactions (1 result)

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EC NUMBER
LITERATURE
REACTION DIAGRAM
REACTION
ENZYME 3D STRUCTURE
show the reaction diagram
GTP + G418 = GDP + G418 2''-phosphate
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Product in Enzyme-catalyzed Reactions (1 result)

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EC NUMBER
LITERATURE
REACTION DIAGRAM
REACTION
ENZYME 3D STRUCTURE
-
show the reaction diagram
S-adenosyl-L-methionine + gentamicin X2 = S-adenosyl-L-homocysteine + G418
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Inhibitor in Enzyme-catalyzed Reactions (1 result)

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COMMENTARY
EC NUMBER
LITERATURE
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

References & Links

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Links to other databases for G418

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ChEBI
PubChem
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PubChem