Any feedback?
Please rate this page
(ligand.php)
(0/150)

BRENDA support

Ligand pantothenate

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

Basic Ligand Information

Molecular Structure
Picture of pantothenate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C9H17NO5
pantothenate
GHOKWGTUZJEAQD-ZETCQYMHSA-N
Synonyms:
(R)-pantothenate, D-pantothenate, pantothenic acid


Show all pahtways known for Show all BRENDA pathways known for pantothenate

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (118 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
pantothenic acid + H2O = ?
show the reaction diagram
-

In Vivo Product in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
ATP + (R)-pantoate + beta-alanine = AMP + diphosphate + (R)-pantothenate
show the reaction diagram
ATP + (R)-pantoate + beta-alanine = ADP + phosphate + (R)-pantothenate
show the reaction diagram
-

Substrate in Enzyme-catalyzed Reactions (317 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
ATP + pantothenate = ADP + 4'-phosphopantothenate
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (20 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
ketopantoate + ? = pantothenate + ?
show the reaction diagram
-
pantetheine + O2 = pantothenate + cysteamine
show the reaction diagram
-
ATP + (R)-pantoate + beta-alanine = ADP + phosphate + (R)-pantothenate
show the reaction diagram
-

Activator in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
contains 3.5 mol pantothenate per mol of enzyme in the acyl-carrier-protein gamma-subunit
-

Inhibitor in Enzyme-catalyzed Reactions (20 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
0.5 mM or above
-
potent inhibitor
-
50 mM, 60% inhibition
-
strong product inhibition
-

3D Structure of Enzyme-Ligand-Complex (PDB) (53 results)

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (9 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.21
-
42°C

KM Value (41 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
1.3
-
42°C

Ki Value (4 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.0439
-
at pH 7.8 and 25°C

References & Links

Links to other databases for pantothenate

ChEBI
PubChem
ChEBI
PubChem