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Ligand 4-methylumbelliferyl-alpha-iduronide 2-sulfate

Basic Ligand Information

Molecular Structure

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Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (2 results)

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Show Substrate (2 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

3.1.6.13

4-methylumbelliferyl-alpha-iduronide 2-sulfate + H2O = 4-methylumbelliferyl-alpha-iduronide + sulfate

699379

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3.1.6.13

4-methylumbelliferyl-alpha-iduronide-2-sulfate + H2O = 4-methylumbelliferyl-alpha-iduronide + sulfate

691079, 707017, 709793

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3.1.6.13

2 entries

Enzyme Kinetic Parameters

References & Links

Literature References (4)

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Show Reference (4 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

691079

18675343

Gene therapy of Hunter syndrome: evaluation of the efficiency of muscle electro gene transfer for the production and release of recombinant iduronate-2-sulfatase (IDS)

2008

Friso, A.; Tomanin, R.; Zanetti, A.; Mennuni, C.; Calvaruso, F.; La Monica, N.; Marin, O.; Zacchello, F.; Scarpa, M.

Biochim. Biophys. Acta

1782

574-580

699379

18500569

Molecular analysis of the iduronate-2-sulfatase gene in Thai patients with Hunter syndrome

2008

Keeratichamroen, S.; Ketudat Cairns, J.R.; Wattanasirichaigoon, D.; Wasant, P.; Ngiwsara, L.; Suwannarat, P.; Pangkanon, S.; Kuptanon, J.; Tanpaiboon, P.; Rujirawat, T.; Liammongkolkul, S.; Svasti, J.

J. Inherit. Metab. Dis.

Suppl. 2

303-311

707017

-

Laboratory scale production of the human recombinant iduronate 2-sulfate sulfatase-Like from Pichia pastoris

2009

Cordoba-Ruiz, H.; Poutou-Pinales, R.; Echeverri-Pena, O.; Algecira-Enciso, N.; Landazuri, P.; Saenz, H.; Barrera-Avellaneda, L.

Afr. J. Biotechnol.

8

1786-1792

709793

19761845

A novel functional role of iduronate-2-sulfatase in zebrafish early development

2010

Moro, E.; Tomanin, R.; Friso, A.; Modena, N.; Tiso, N.; Scarpa, M.; Argenton, F.

Matrix Biol.

29

43-50

Links to other databases for 4-methylumbelliferyl-alpha-iduronide 2-sulfate

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ChEBI

PubChem

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