Ligand (+)-5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine

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Basic Ligand Information

Molecular Structure
Picture of (+)-5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C16H15N
(+)-5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine
LBOJYSIDWZQNJS-CVEARBPZSA-N
Synonyms:
MK-801, MK801

Roles as Enzyme Ligand

Activator in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
MK-801, a dose-dependent elevation in the expression of DAO mRNA is observed in most brain areas 4 h after the administration (1.6 mg/kg)
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drug acting on glutamatergic receptor type enhances AAAD activity
-
N-methyl-D-aspartate-type glutamate receptor antagonist, activates the enzyme and inhibits osteogenic differentiation of the rat bone marrow stem cells
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Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
MK-801, a drastic decline in the expression of DAO mRNA is observed in most brain areas 1 h after the MK-801 administration (1.6 mg/kg)
-

Enzyme Kinetic Parameters

References & Links

Links to other databases for (+)-5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine

ChEBI
PubChem
ChEBI
PubChem