Ligand bromocriptine

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Basic Ligand Information

Molecular Structure
Picture of bromocriptine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C32H40BrN5O5
bromocriptine
OZVBMTJYIDMWIL-AYFBDAFISA-N
Synonyms:
bromocryptine

Show all pahtways known for Show all pathways known for bromocriptine

Roles as Enzyme Ligand

Activator in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
significantly upregulates expression and activity (911% of untreated control) of NQO1, attenuates increase in protein-bound quinone in H2O2-treated PC12 cells, and protects PC12 cells against oxidative damage. Bromocriptine increases the expression and nuclear translocation of a basic leucine zipper transcription factor Nrf2, involved in the regulation of the enzyme
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Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
reduced AAAD activity in the striatum by acute and chronic treatment with the D2-like receptor agonist
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Enzyme Kinetic Parameters

References & Links

Links to other databases for bromocriptine

ChEBI
PubChem
ChEBI
PubChem