Ligand benzaldehyde

(1E)-2-methyl-4-(2,6,6-trimethylcyclohex-1-en-1-yl)but-1-en-1-yl benzoate + O2 = 4-(2,6,6-trimethylcyclohex-1-en-1-yl)butan-2-one + CO2 + benzaldehyde

1.2.1.30

7 entries

1.2.3.9

2 entries

1.2.7.5

benzoate + Ti(III) citrate + 2 H+ = benzaldehyde + Ti(I) citrate + H2O

1.4.1.28

2 entries

1.4.3.10

benzylamine + O2 + H2O = benzaldehyde + NH3 + H2O2

1.4.3.12

benzylamine + O2 + H2O = benzaldehyde + NH3 + H2O2

1.4.3.13

benzylamine + O2 + H2O = benzaldehyde + NH3 + H2O2

benzylamine + H2O + O2 = benzaldehyde + NH3 + H2O2

1.5.99.12

N-benzyladenine + electron acceptor = benzaldehyde + adenine + reduced electron acceptor

phenylamine + 2-oxoglutarate = benzaldehyde + L-glutamate

2.6.1.116

benzylamine + pyruvate = benzaldehyde + L-alanine

2.6.1.18

2-oxobutyrate + benzylamine = L-homoalanine + benzaldehyde

2.6.1.B16

pyruvate + benzylamine = L-alanine + benzaldehyde

3.2.1.117

2 entries

3.7.1.8

2,6-dihydroxy-6-phenylhexa-2,4-dienoate = benzaldehyde + (2E)-2-hydroxypenta-2,4-dienoic acid

oxo(phenyl)acetic acid = benzaldehyde + CO2

benzylidenepyruvate + H2O = benzaldehyde + pyruvate

D-beta-phenylserine = glycine + benzaldehyde

4.1.3.39

4-hydroxy-2-oxo-4-benzylbutanoate = benzaldehyde + pyruvate

Activator in Enzyme-catalyzed Reactions (1 result)

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4.1.2.38

no activity with 200 mg m/L benzaldehyde. Reaction conducted with 50 mg benzaldehyde results in a 90% conversion after 45 min

706034

Inhibitor in Enzyme-catalyzed Reactions (32 results)

50% inhibition at 2 mM

slight inhibition

substrate inhibition

substrate inhibition

1 mM, 51% inhibition

substrate inhibition at high concentrations

740765

4us8, 3D-view

1.4.3.4

strong competitive inhibitor

723891

2.2.1.6

inhibits isozyme AHAS II, not isozyme AHAS I

672368

2.4.1.85

potent inhibitor, 1 mg/ml bovine serum albumin protects

greatly inhibits the enzyme activity

competitive inhibition

718924

3.5.5.1

nearly complete inhibition at 10 mM

leads to a complete and irreversible deactivation of the enzyme within 2 h incubation

5143

4.1.2.47

3 entries

3D Structure of Enzyme-Ligand-Complex (PDB) (74 results)

Enzyme Kinetic Parameters

k_cat Value (Turnover Number) (130 results)

54.4

pH 7.0, 25Â°C

738059

1.1.1.283

1.05

1 mM

0.5

wild type enzyme, at 24Â°C, 0.1 M sodium phosphate buffer, pH 6.0

0.9

100 mM H2NaPO4 pH 7.5, 100 mM NaCl, 20 mM 2-mercaptoethanol, 2 mM NAD+

0.2

wild-type

671851

1.2.1.39

0.16

pH 7.5

670833

1.2.1.4

4.52

pH 8.4, 28Â°C, cosubstrate NADP+

26.4

pH 8.0, temperature not specified in the publication

741638

1.2.1.7

4.6

apparent Kcat

697657

1.2.1.77

0.019

in 50 mM Tris-HCl (pH 7.5), at 25Â°C

688414

1.2.1.99

17.37

pH 8.0, 37Â°C, cofactor: NAD+

0.000001

pH 7.5, K133Q/T161K mutant

K_M Value (252 results)

1.05

5.2

pH 7.0, 25Â°C

738059

1.1.1.283

1.69

1 mM

670170

1.1.1.431

1.8

pH 7.2, temperature not specified in the publication

721903

1.1.1.71

15.6

at pH 7.5 and 30Â°C

wild type enzyme, at 24Â°C, 0.1 M sodium phosphate buffer, pH 6.0

0.00023

0.15

100 mM H2NaPO4 pH 7.5, 100 mM NaCl, 20 mM 2-mercaptoethanol, 2 mM NAD+

0.46

0.008

pH 7.5

1.44

0.001

pH 8.0, temperature not specified in the publication

0.32

4.15

in 50 mM Tris-HCl (pH 7.5), at 25Â°C

0.46

in 100 mM glycine-NaOH (pH 9.2), at 25Â°C

390225

1.2.1.88

0.5

isoform A

392065

1.2.1.99

5.37

pH 8.0, 37Â°C, cofactor: NAD+

0.395

70Â°C, pH 8.0

26.3

pH 7.5, K133Q/T161K mutant

8.98

at pH 7.0, 30Â°C

714354

4.1.2.47

9 entries

K_i Value (13 results)

pH 6.1, 30Â°C

0.306

pH 8.0, temperature not specified in the publication

0.7

0.8

Kis value, pH 7.6, 35Â°C

740765

1.4.3.4

0.003

at pH 7.0 and 37Â°C

723891

2.2.1.6

1.4

isozyme AHAS II

672368

3.5.1.19

0.0206

wild type enzyme, in 50 mM sodium phosphate (pH 7.5), at 25Â°C

718924

4.1.2.47

2 entries

IC₅₀ Value (1 result)

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1.14.18.1

0.8

699195

References & Links

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Show Reference (502 entries)

Ligand benzaldehyde

Basic Ligand Information

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (19 results)

In Vivo Product in Enzyme-catalyzed Reactions (23 results)

Substrate in Enzyme-catalyzed Reactions (259 results)

Product in Enzyme-catalyzed Reactions (147 results)

Activator in Enzyme-catalyzed Reactions (1 result)

Inhibitor in Enzyme-catalyzed Reactions (32 results)

3D Structure of Enzyme-Ligand-Complex (PDB) (74 results)

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (130 results)

KM Value (252 results)

Ki Value (13 results)

IC50 Value (1 result)

References & Links

Literature References (502)

k_cat Value (Turnover Number) (130 results)

K_M Value (252 results)

K_i Value (13 results)

IC₅₀ Value (1 result)