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BRENDA support

Ligand A

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Basic Ligand Information

Molecular Structure
Picture of A (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
HR
A
Synonyms:
oxidized donor, oxidized putidaredoxin, R1H, RH


Show all pahtways known for Show all BRENDA pathways known for A

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (13 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
RH + [reduced NADPH-hemoprotein reductase] + O2 = ROH + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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C-terminal [mycofactocin precursor peptide MftA]-glycyl-3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidin-2-one + 5'-deoxyadenosine + L-methionine + A = C-terminal [mycofactocin precursor peptide]-glycyl-L-valyl-4-[2-aminoethenyl]phenol + S-adenosyl-L-methionine + AH2
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (85 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
donor + H2O2 = oxidized donor + 2 H2O
show the reaction diagram
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fumitremorgin B + 2-oxoglutarate + 2 O2 + AH2 = verruculogen + succinate + CO2 + H2O + A
show the reaction diagram
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L-tyrosine + O2 + AH2 = L-3,4-dihydroxyphenylalanine + H2O + A
show the reaction diagram
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O-1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine + AH2 + O2 = O-1-alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + A + 2 H2O
show the reaction diagram
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androst-4-ene-3,17-dione + AH2 + O2 = 3-oxo-13,17-secoandrost-4-ene-17,13alpha-lactone + A + H2O
show the reaction diagram
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4-methoxybenzoate + AH2 + O2 = 4-hydroxybenzoate + formaldehyde + A + H2O
show the reaction diagram
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Latia luciferin + AH2 + O2 = oxidized Latia luciferin + CO2 + formate + A + H2O + hnu
show the reaction diagram
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ecdysone + AH2 + O2 = 20-hydroxyecdysone + A + H2O
show the reaction diagram
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progesterone + AH2 + O2 = 9alpha-hydroxyprogesterone + A + H2O
show the reaction diagram
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thiophene-2-carbonyl-CoA + AH2 + O2 = 5-hydroxythiophene-2-carbonyl-CoA + A + H2O
show the reaction diagram
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cholesterol + AH2 + O2 = 25-hydroxycholesterol + A + H2O
show the reaction diagram
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ammonia + AH2 + O2 = NH2OH + A + H2O
show the reaction diagram
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[(1->4)-beta-D-glucosyl]n+m + AH2 + O2 = [(1->4)-beta-D-glucosyl]m-1-(1->4)-D-glucono-1,5-lactone + [(1->4)-beta-D-glucosyl]n + A + H2O
show the reaction diagram
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starch + AH2 + O2 = aldonic acid-terminated malto-oligosaccharides + A + H2O
show the reaction diagram
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heme + 3 AH2 + 3 O2 = biliverdin + Fe2+ + CO + 3 A + 3 H2O
show the reaction diagram
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2,3-epoxyphylloquinone + AH2 = phylloquinone + A + ?
show the reaction diagram
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reduced putidaredoxin + NAD+ = oxidized putidaredoxin + NADH + H+
show the reaction diagram
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chlorophyllide a + AH2 + ATP + H2O = 3-deacetyl-3-vinylbacteriochlorophyllide a + A + ADP + phosphate
show the reaction diagram
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AH2 + chlorate = A + H2O + chlorite
show the reaction diagram
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C-terminal [mycofactocin precursor peptide]-glycyl-L-valyl-4-[2-aminoethenyl]phenol + S-adenosyl-L-methionine + AH2 = C-terminal [mycofactocin precursor peptide]-glycyl-3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidin-2-one + 5'-deoxyadenosine + L-methionine + A
show the reaction diagram
-

Substrate in Enzyme-catalyzed Reactions (20 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
RH + [reduced NADPH-hemoprotein reductase] + O2 = ROH + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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3,3',5'-triido-L-thyronine + iodide + A + H+ = L-thyroxine + AH2
show the reaction diagram
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3,5,3'-triiodo-L-thyronine + iodide + A + H+ = L-thyroxine + AH2
show the reaction diagram
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succinate + oxidized donor = ?
show the reaction diagram
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C-terminal [mycofactocin precursor peptide MftA]-glycyl-3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidin-2-one + 5'-deoxyadenosine + L-methionine + A = C-terminal [mycofactocin precursor peptide]-glycyl-L-valyl-4-[2-aminoethenyl]phenol + S-adenosyl-L-methionine + AH2
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (259 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
donor + H2O2 = oxidized donor + 2 H2O
show the reaction diagram
-
fumitremorgin B + 2-oxoglutarate + 2 O2 + AH2 = verruculogen + succinate + CO2 + H2O + A
show the reaction diagram
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styrene + O2 + reduced putidaredoxin = (S)-styrene oxide + 2-phenylethanol + oxidized putidaredoxin + H2O
show the reaction diagram
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(+)-camphor + reduced putidaredoxin + O2 = (+)-6-endo-hydroxycamphor + oxidized putidaredoxin + H2O
show the reaction diagram
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palmitoyl-[acyl-carrier protein] + AH2 + O2 = palmitoleoyl-[acyl-carrier protein] + A + H2O
show the reaction diagram
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tetradecanoic acid + O2 + AH2 = (11E)-tetradec-11-enoic acid + A + H2O
show the reaction diagram
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O-1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine + AH2 + O2 = O-1-alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + A + 2 H2O
show the reaction diagram
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Latia luciferin + AH2 + O2 = oxidized Latia luciferin + CO2 + formate + A + H2O + hnu
show the reaction diagram
-
ecdysone + AH2 + O2 = 20-hydroxyecdysone + A + H2O
show the reaction diagram
-
progesterone + AH2 + O2 = 9alpha-hydroxyprogesterone + A + H2O
show the reaction diagram
-
thiophene-2-carbonyl-CoA + AH2 + O2 = 5-hydroxythiophene-2-carbonyl-CoA + A + H2O
show the reaction diagram
-
cholesterol + AH2 + O2 = 25-hydroxycholesterol + A + H2O
show the reaction diagram
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ammonia + AH2 + O2 = NH2OH + A + H2O
show the reaction diagram
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(+)-larreatricin + O2 + AH2 = (+)-3-hydroxylarreatricin + A + H2O
show the reaction diagram
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starch + AH2 + O2 = aldonic acid-terminated malto-oligosaccharides + A + H2O
show the reaction diagram
-
heme + 3 AH2 + 3 O2 = biliverdin + Fe2+ + CO + 3 A + 3 H2O
show the reaction diagram
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2,3-epoxyphylloquinone + AH2 = phylloquinone + A + ?
show the reaction diagram
-
fumarate + electron donor = succinate + oxidized donor
show the reaction diagram
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chlorophyllide a + AH2 + ATP + H2O = 3-deacetyl-3-vinylbacteriochlorophyllide a + A + ADP + phosphate
show the reaction diagram
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AH2 + chlorate = A + H2O + chlorite
show the reaction diagram
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selenate + electron donor = selenite + H2O + oxidized donor
show the reaction diagram
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FVNQHLCGSHLVEALYLVCGERGFFYTPKA + H2O = FVNQHLCGSHLVE + A + LYLVCGERGF + FY + TPKA
show the reaction diagram
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C-terminal [mycofactocin precursor peptide]-glycyl-L-valyl-4-[2-aminoethenyl]phenol + S-adenosyl-L-methionine + AH2 = C-terminal [mycofactocin precursor peptide]-glycyl-3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidin-2-one + 5'-deoxyadenosine + L-methionine + A
show the reaction diagram
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RHg+ + H+ = RH + Hg2+
show the reaction diagram
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Enzyme Kinetic Parameters

References & Links

Links to other databases for A

ChEBI
PubChem
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