Ligand 16,17alpha-epoxyprogesterone
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Basic Ligand Information
Molecular Structure

C21H28O3
16,17alpha-epoxyprogesterone
LHNVKVKZPHUYQO-CWNZLVRBSA-N
Roles as Enzyme Ligand
In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
16,17alpha-epoxyprogesterone + reduced adrenal ferredoxin + O2 = 11beta-hydroxy-16,17alpha-epoxyprogesterone + adrenal ferredoxin + H2O
-
Substrate in Enzyme-catalyzed Reactions (3 results)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
16,17alpha-epoxyprogesterone + reduced adrenal ferredoxin + O2 = 11beta-hydroxy-16,17alpha-epoxyprogesterone + adrenal ferredoxin + H2O
-
16,17alpha-epoxyprogesterone + AH2 + O2 = 11alpha-hydroxy-16,17alpha-epoxyprogesterone + A + H2O
-
16,17alpha-epoxyprogesterone + acceptor = ? + reduced acceptor
-
Enzyme Kinetic Parameters
kcat Value (Turnover Number) (1 result)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
13849.8
-
recombinant enzyme, pH 8.0, 40°C
KM Value (1 result)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
0.0305
-
recombinant enzyme, pH 8.0, 40°C
References & Links
Literature References (3)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
-
The 11beta-hydroxylation of 16,17alpha-epoxyprogesterone and the purification of the 11beta-hydroxylase from Absidia coerulea IBL02
2007
Chen, K.; Tong, W.; Wei, D.; Jiang, W.
Enzyme Microb. Technol.
41
71-79
Cloning and identification of a novel steroid 11alpha-hydroxylase gene from Absidia coerulea
2017
Wang, R.; Sui, P.; Hou, X.; Cao, T.; Jia, L.; Lu, F.; Singh, S.; Wang, Z.; Liu, X.
J. Steroid Biochem. Mol. Biol.
171
254-261
Purification, characterization, and application of a high activity 3-ketosteroid-DELTA1-dehydrogenase from Mycobacterium neoaurum DSM 1381
2019
Zhang, R.; Xu, X.; Cao, H.; Yuan, C.; Yuminaga, Y.; Zhao, S.; Shi, J.; Zhang, B.
Appl. Microbiol. Biotechnol.
103
6605-6616
Links to other databases for 16,17alpha-epoxyprogesterone