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Ligand 5-methylbenzimidazole

Basic Ligand Information

Molecular Structure

Related pathways

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Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (1 result)

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Show Substrate (1 entry)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.4.2.21

beta-nicotinate D-ribonucleotide + 5-methylbenzimidazole = nicotinate + N1-(5-phospho-alpha-D-ribosyl)-5-methylbenzimidazole

735924, 735682

1jhm, 3D-view

Inhibitor in Enzyme-catalyzed Reactions (1 result)

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Show Inhibitors (1 entry)

EC NUMBER

COMMENTARY

LITERATURE

ENZYME 3D STRUCTURE

1.17.3.2

poor inhibitor

685516

-

3D Structure of Enzyme-Ligand-Complex (PDB) (1 result)

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Show 3D Structure of Enzyme-Ligand-Complex (PDB) (1 entry)

EC NUMBER

ENZYME 3D STRUCTURE

2.4.2.21

1jhm, 3D-view

Enzyme Kinetic Parameters

References & Links

Literature References (3)

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Show Reference (3 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

685516

17379526

The screening and characterization of 6-aminopurine-based xanthine oxidase inhibitors

2007

Hsieh, J.F.; Wu, S.H.; Yang, Y.L.; Choong, K.F.; Chen, S.T.

Bioorg. Med. Chem.

15

3450-3456

735682

25412146

Regiospecific formation of cobamide isomers is directed by CobT

2014

Crofts, T.S.; Hazra, A.B.; Tran, J.L.; Sokolovskaya, O.M.; Osadchiy, V.; Ad, O.; Pelton, J.; Bauer, S.; Taga, M.E.

Biochemistry

53

7805-7815

735924

24055007

Cobamide structure depends on both lower ligand availability and CobT substrate specificity

2013

Crofts, T.S.; Seth, E.C.; Hazra, A.B.; Taga, M.E.

Chem. Biol.

20

1265-1274

Links to other databases for 5-methylbenzimidazole

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