Ligand methyl gallate

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Basic Ligand Information

Molecular Structure
Picture of methyl gallate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C8H8O5
methyl gallate
FBSFWRHWHYMIOG-UHFFFAOYSA-N
Synonyms:
3,4,5-trihydroxybenzoic acid methylester, 3,4,5-trihydroxybenzoic acid methyl ester, Gallic acid methylester, Gallic acid methyl ester, Methyl 3,4,5-trihydroxybenzoate, methylgallate

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
methyl gallate + H2O = gallic acid + methanol
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (11 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
S-adenosyl-L-methionine + methyl gallate = S-adenosyl-L-homocysteine + ?
show the reaction diagram
-
methyl gallate = ?
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
gallate + methanol = methyl gallate + H2O
show the reaction diagram
-
-

Inhibitor in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
shows a concentration-dependent inhibitory activity against tyrosinase with IC50 of 0.0625 mg/ml
-
slight inhibition
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (28 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
80.2
-
-
0.23
-
-

KM Value (48 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.96
-
-

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.008
-
presence of MnCl2, overnight (15 h) pre-incubation of compound and enzyme before initiation of the reaction with GDP-fucose

References & Links

Links to other databases for methyl gallate

ChEBI
PubChem
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PubChem